Capanna R, Bertoni F, Bettelli G, Picci P, Bacchini P, Present D, Giunti A, Campanacci M
1st Orthopaedic Clinic, Istituto Ortopedico Rizzoli, Bologna, Italy.
J Bone Joint Surg Am. 1988 Jan;70(1):60-9.
The cases of forty-six patients who had dedifferentiated chondrosarcoma were reviewed. Two groups were identified: one in which a low-grade malignant chondrosarcoma was the precursor lesion and one in which a moderate to high-grade malignant chondrosarcoma was the precursor lesion. The radiographic features of these lesions ranged from that of a cartilaginous lesion that appeared to be benign to that of a destructive osteolytic tumor in which the cartilaginous component was overshadowed by the dedifferentiated component. Only three of the forty-six patients survived for more than two years. Resection alone, even when it was wide or radical, was not successful in controlling this lethal sarcoma.
回顾了46例去分化软骨肉瘤患者的病例。确定了两组：一组以低度恶性软骨肉瘤为前驱病变，另一组以中度至高度恶性软骨肉瘤为前驱病变。这些病变的影像学特征范围从看似良性的软骨病变到破坏性溶骨性肿瘤，其中软骨成分被去分化成分掩盖。46例患者中只有3例存活超过两年。单纯切除，即使是广泛或根治性切除，也未能成功控制这种致命的肉瘤。
