Forsström J, Viander M, Lehtonen A, Ekfors T
Scand J Infect Dis. 1977;9(3):253-6. doi: 10.3109/inf.1977.9.issue-3.21.
A case of mild glomerulonephritis in a 24-year-old man with clinical and immunohistological findings associated with Yersinia enterocolitica serotype 3 infection is described. The role of IgA in the pathogenesis of glomerulonephritis associated with mucosal infection is briefly discussed. Although attempts to demonstrate Y. enterocolitica 3 antigen in the biopsy specimen were unsuccessful, the glomerular deposits of immunoglobulins and complement suggest immune pathogenesis.
本文描述了一例24岁男性的轻度肾小球肾炎病例,其临床和免疫组织学检查结果与3型小肠结肠炎耶尔森菌感染相关。简要讨论了IgA在与黏膜感染相关的肾小球肾炎发病机制中的作用。尽管在活检标本中未能成功检测到3型小肠结肠炎耶尔森菌抗原,但免疫球蛋白和补体在肾小球中的沉积提示了免疫发病机制。