School of Clinical Medicine, Beijing University of Chinese Medicine, Beijing, China.
Department of Dermatology, China-Japan Friendship Hospital, Beijing, China.
J Cosmet Dermatol. 2021 Aug;20(8):2538-2541. doi: 10.1111/jocd.13904. Epub 2021 Jan 6.
Alopecia for patients with discoid lupus erythematosus can sometimes be a refractory condition, where mixed infiltrates of T lymphocytes and histiocytes leads to destruction of hair follicles, which might cause permanent scarring. Early diagnosis and timely treatment can achieve hair regeneration and prevent further disease progression. Concentrated growth factor, a novel autologous plasma extract, contains various growth factors that could promote tissue regeneration. In this article, we report a case of cell growth factor combined with corticosteroids for the treatment of discoid lupus erythematosus alopecia. This case study concludes with satisfactory clinical effect.
盘状红斑狼疮患者的脱发有时可能是一种难治性疾病,其中 T 淋巴细胞和组织细胞的混合浸润导致毛囊破坏,可能导致永久性瘢痕。早期诊断和及时治疗可以实现毛发再生,防止疾病进一步进展。浓缩生长因子是一种新型的自体血浆提取物,含有多种可促进组织再生的生长因子。本文报道了一例细胞生长因子联合皮质类固醇治疗盘状红斑狼疮脱发的病例。该病例研究得出了满意的临床效果。