Chen Xiang, Zheng Lei, Chen Da-Ke
Department of Urology, Wenzhou People's Hospital, Wenzhou, Zhejiang 325000, China.
Zhonghua Nan Ke Xue. 2020 Jun;26(6):553-558.
To evaluate the inhibitory effect of Ningmitai Capsules (NMTC) on the proliferation and in vitro biofilm formation of Staphylococcus sp. and Escherichia coli (E. coli).
Using the gradient dilution method, we determined the minimum inhibitory concentration (MIC) of NMTC against Staphylococcus epidermidis (S. epidermids) 1457, Staphylococcus aureus (S. aureus) NCTC8325-4/ Newman/ MU50 and E. coli ATCC25922/ CF073, and observed the effects of different concentrations of NMTC on their biofilm formation in vitro under the electron microscope.
NMTC significantly suppressed the proliferation of S. epidermidis 1457, S. aureus NCTC8325-4/ Newman/ MU50 and E. coli ATCC25922/CF073 at an MIC of 20 mg/ml as well as their biofilm formation in vitro.
Ningmitai Capsules can inhibit the proliferation and in vitro biofilm formation of S. epidermids and E. coli, and has a comprehensive antibacterial effect.
评价宁米泰胶囊（NMTC）对葡萄球菌属和大肠杆菌（E. coli）增殖及体外生物膜形成的抑制作用。
采用梯度稀释法测定NMTC对表皮葡萄球菌（S. epidermids）1457、金黄色葡萄球菌（S. aureus）NCTC8325 - 4/纽曼/MU50和大肠杆菌ATCC25922/CF073的最低抑菌浓度（MIC），并在电子显微镜下观察不同浓度NMTC对其体外生物膜形成的影响。
NMTC在20 mg/ml的MIC浓度下显著抑制表皮葡萄球菌1457、金黄色葡萄球菌NCTC8325 - 4/纽曼/MU50和大肠杆菌ATCC25922/CF073的增殖及其体外生物膜形成。
宁米泰胶囊可抑制表皮葡萄球菌和大肠杆菌的增殖及体外生物膜形成，具有综合抗菌作用。
