Department of Chemistry, The University of Manchester, Oxford Road, Manchester M13 9PL, United Kingdom.
Mettler-Toledo Ltd., 64 Boston Road, Beaumont Leys, Leicester LE4 1AW, United Kingdom.
J Org Chem. 2021 Jan 15;86(2):2012-2016. doi: 10.1021/acs.joc.0c02684. Epub 2020 Dec 24.
FTIR spectroscopy is a common in situ reaction monitoring technique used in modern academic and industrial environments. The FTIR signals collected during the course of a reaction are proportional to the concentration of the reaction components but not intrinsically quantitative. To make FTIR data quantitative, precalibration or offline analyses of reaction samples are required, which diminishes the unique benefits of in situ reaction monitoring techniques. Herein, we report the use of standard addition as a convenient method to obtain quantitative FTIR data.
傅里叶变换红外光谱（FTIR）是现代学术和工业环境中常用的原位反应监测技术。在反应过程中收集的 FTIR 信号与反应组分的浓度成正比，但不是本质上的定量。为了使 FTIR 数据具有定量性，需要对反应样品进行预校准或离线分析，这降低了原位反应监测技术的独特优势。在此，我们报告了使用标准添加作为获得定量 FTIR 数据的便捷方法。
