Unit of Public Health and Environmental Care. Department of Preventive Medicine and Public Health, Food Sciences, Toxicology and Legal Medicine, School of Pharmacy, Universitat de Valencia, Burjassot, Valencia, Spain.
Biomedical Research Center Network for Epidemiology and Public Health (CIBERESP), Madrid, Madrid, Spain.
Nutr Cancer. 2022;74(1):39-54. doi: 10.1080/01635581.2020.1865422. Epub 2020 Dec 26.
It is suspected that diet influences the risk of developing breast cancer. Several β-carotenoids have been inversely associated with breast cancer risk, but association by type of tumor and participant characteristics remain nuclear. The objective of this review of epidemiological studies is to investigate the relationship between β-carotenoids and breast cancer. This review covers the 2014-2020 period and was carried out using the PubMed and EMBASE databases. Only epidemiological studies carried out on β-carotenoids and breast cancer were included. The initial keyword search yielded 1559 results and finally a total of 28 studies were included. The quality of the articles and the risk of bias for each included article were assessed. The selected articles were subsequently classified according to their quality. The evidence from the included studies confirms that there is an association between β-carotenoids and breast cancer risk; the dietary intake of β-carotenoids may be beneficial in reducing the risk of developing breast cancer.
人们怀疑饮食会影响乳腺癌的发病风险。有几种β-胡萝卜素与乳腺癌风险呈负相关，但肿瘤类型和参与者特征的相关性仍不明确。本综述旨在调查β-胡萝卜素与乳腺癌之间的关系。本综述涵盖了 2014-2020 年期间，使用 PubMed 和 EMBASE 数据库进行了检索。仅纳入了关于β-胡萝卜素和乳腺癌的流行病学研究。最初的关键词搜索得到了 1559 个结果，最终共有 28 项研究被纳入。评估了文章的质量和每篇纳入文章的偏倚风险。随后根据文章的质量对选定的文章进行了分类。纳入研究的证据证实了β-胡萝卜素与乳腺癌风险之间存在关联；β-胡萝卜素的饮食摄入可能有助于降低患乳腺癌的风险。
