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[一名接受血液透析的慢性肾衰竭患者出现迟发性皮肤卟啉症样大疱性皮肤病]

[Porphyria cutanea tarda-like bullous dermatosis in a patient with chronic renal failure under hemodialysis].

作者信息

Rufli T, Brunner F

出版信息

Schweiz Med Wochenschr. 1977 Aug 6;107(31):1093-6.

PMID:333570
Abstract

Patients with chronic renal failure under regular hemodialysis may present porphyria cutanea tarda-like dermatoses without, however, exhibiting a disturbed porphyrin metabolism. Based on a personal observation and the literature the anamnestic, clinical and histological features of this distinct dermatosis are discussed. Metabolic disturbances due to chronic renal failure, with or without hemodialysis, are possible etiopathogenetic factors, while in the light of the latest findings it seems improbable that any such role is played by frusemide therapy.

摘要

接受定期血液透析的慢性肾衰竭患者可能会出现迟发性皮肤卟啉病样皮肤病,但卟啉代谢并无紊乱。基于个人观察和文献,对这种独特皮肤病的既往史、临床和组织学特征进行了讨论。慢性肾衰竭导致的代谢紊乱,无论是否进行血液透析,都是可能的病因学因素,而根据最新研究结果,速尿治疗似乎不太可能起到这样的作用。

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