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青少年 COVID-19 相关致死性横纹肌溶解症。

Adolescent COVID-19-Associated Fatal Rhabdomyolysis.

机构信息

Primary Health Care, Muscat Governorate, Ministry of Health, Oman.

出版信息

J Prim Care Community Health. 2020 Jan-Dec;11:2150132720985641. doi: 10.1177/2150132720985641.

Abstract

Coronavirus disease 2019 (COVID-19) has become an urgent global health priority. Although most patients with COVID-19 manifest with fever and respiratory tract symptoms, COVID-19 infections may also involve other organs and extrarespiratory manifestations, including cardiac, gastrointestinal, hepatic, renal, and neurological symptoms. This case describes a 16-year-old boy who presented with fever, sore throat, myalgia, and subsequently with shortness of breath. A diagnosis of COVID-19 was confirmed by polymerase chain reaction. His condition deteriorated and he died within 3 days of admission. An evaluation of his past medical history confirmed an episode of viral illness which had progressed to myositis and rhabdomyolysis 1 year prior. Clinicians should be aware of this complication and maintain a high index of suspicion in cases of COVID-19 presenting with extrapulmonary symptoms.

摘要

新型冠状病毒病 2019(COVID-19)已成为一项紧迫的全球卫生重点。尽管大多数 COVID-19 患者表现为发热和呼吸道症状,但 COVID-19 感染也可能涉及其他器官和非呼吸道表现,包括心脏、胃肠道、肝脏、肾脏和神经系统症状。本病例描述了一名 16 岁男孩,他出现发热、咽痛、肌痛,随后出现呼吸急促。聚合酶链反应证实了 COVID-19 的诊断。他的病情恶化,入院后 3 天内死亡。对其既往病史的评估证实,1 年前他曾患过病毒性疾病,病情进展为肌炎和横纹肌溶解症。临床医生应注意这种并发症,并对出现非肺部症状的 COVID-19 保持高度怀疑。

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Adolescent COVID-19-Associated Fatal Rhabdomyolysis.青少年 COVID-19 相关致死性横纹肌溶解症。
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本文引用的文献

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COVID-19 and Rhabdomyolysis.新型冠状病毒肺炎与横纹肌溶解症
J Gen Intern Med. 2020 Oct;35(10):3087-3090. doi: 10.1007/s11606-020-06039-y. Epub 2020 Jul 15.
4
Pediatric COVID-19-associated rhabdomyolysis: a case report.儿童 COVID-19 相关横纹肌溶解症:病例报告。
Pediatr Nephrol. 2020 Aug;35(8):1517-1520. doi: 10.1007/s00467-020-04617-0. Epub 2020 May 23.
5
Myositis as a manifestation of SARS-CoV-2.肌炎作为严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的一种表现形式。
Ann Rheum Dis. 2021 Mar;80(3):e42. doi: 10.1136/annrheumdis-2020-217573. Epub 2020 Apr 23.
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Clinical Characteristics of Coronavirus Disease 2019 in China.《中国 2019 年冠状病毒病临床特征》
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Rhabdomyolysis: a genetic perspective.横纹肌溶解症:遗传学视角
Orphanet J Rare Dis. 2015 May 2;10:51. doi: 10.1186/s13023-015-0264-3.
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Rhabdomyolysis and acute kidney injury.横纹肌溶解症与急性肾损伤。
N Engl J Med. 2009 Jul 2;361(1):62-72. doi: 10.1056/NEJMra0801327.

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