Physical Activity and Health Laboratory, Instituto de Investigación Sanitaria Hospital '12 de Octubre' ('imas12'), 28041 Madrid, Spain.
Department of Systems Biology, University of Alcalá, 28041 Madrid, Spain.
Trends Cancer. 2021 Feb;7(2):91-93. doi: 10.1016/j.trecan.2020.12.003. Epub 2021 Jan 6.
Regular exercise reduces the risk of cancer. One potential mechanism for this efficacy is improved antitumor immunity. This is an important issue because evading immune destruction is a hallmark of cancer and immunotherapy is reshaping cancer treatment. Here we review recent developments reported by Wennerberg et al., Garritson et al., Martín-Ruiz et al., and Rundqvist et al. on the effects of exercise on anticancer immune cell effectors.
定期锻炼可降低癌症风险。其发挥作用的一种潜在机制是增强抗肿瘤免疫。这是一个重要问题,因为逃避免疫破坏是癌症的一个标志,而免疫疗法正在改变癌症治疗方式。在此,我们对 Wennerberg 等人、Garritson 等人、Martín-Ruiz 等人和 Rundqvist 等人最近关于运动对抗癌免疫细胞效应物影响的研究进展进行综述。