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基于同步加速器的离子束治疗设施的优化以减少治疗时间、选择和 MedAustron 发展路线图。

Optimization of synchrotron based ion beam therapy facilities for treatment time reduction, options and the MedAustron development roadmap.

机构信息

EBG MedAustron, Wiener Neustadt, Austria.

EBG MedAustron, Wiener Neustadt, Austria.

出版信息

Phys Med. 2021 Jan;81:264-272. doi: 10.1016/j.ejmp.2020.11.029. Epub 2020 Dec 24.

DOI:10.1016/j.ejmp.2020.11.029
PMID:33358290
Abstract

A faster treatment reduces the risk of intra-fraction movement of organs, offers a more comfortable treatment to the patient, allows to treat lesion of larger volumes in a reasonable time and most of all expands the capacity of the facility. This work presents possible machine upgrades for synchrotron based ion beam therapy centers to shorten the irradiation time. The expected delivery times for each scenario are simulated for the study case of proton beams of MedAustron. The second part of the work focuses on the MedAustron development roadmap, where recently increase of ring fillings and delivered intensities were implemented for proton treatments achieving an average irradiation time of ~50% since start of operation.

摘要

更快的治疗可以降低器官在分次内移动的风险,为患者提供更舒适的治疗,允许在合理的时间内治疗更大体积的病变,最重要的是扩大了设施的容量。本工作提出了基于同步加速器的离子束治疗中心的可能的机器升级方案,以缩短照射时间。为了研究 MedAustron 的质子束,对每种情况下的预期交付时间进行了模拟。本工作的第二部分重点介绍了 MedAustron 的发展路线图,最近在质子治疗中增加了环填充和输送强度,自运行开始以来,平均照射时间缩短了约 50%。

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