Suppr超能文献

MAIT 细胞在代谢性疾病中的作用。

Role of MAIT cells in metabolic diseases.

机构信息

Université de Paris, Institut Cochin, INSERM U1016, CNRS UMR 8104, Paris, France.

出版信息

Mol Immunol. 2021 Feb;130:142-147. doi: 10.1016/j.molimm.2020.12.014. Epub 2020 Dec 25.

Abstract

MAIT cells are innate-like T cells that are enriched in mucosal sites and tissues including adipose tissue and liver. They play an important role in immunity against microbial pathogens. Recently, it has been reported that MAIT cells could also be important in metabolic diseases and can be involved in setting up and maintaining chronic inflammation. In this review, we give an overview of recent advances in understanding MAIT cells role in the ethology of this diseases.

摘要

MAIT 细胞是先天样 T 细胞,在包括脂肪组织和肝脏在内的黏膜部位和组织中丰富存在。它们在抵御微生物病原体的免疫中发挥重要作用。最近,据报道 MAIT 细胞在代谢疾病中也很重要,并可能参与慢性炎症的发生和维持。在这篇综述中,我们概述了近年来对 MAIT 细胞在这些疾病发病机制中作用的理解的进展。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验