Wilisch J, Pradere B, Misrai V, Baumert H, Doizi S, Lebdai S, Delongchamps N B, Benchikh A, Negra E D, Fourmarier M, Chevrot A, Rouscoff Y, Theveniaud P E, Vincendeau S, Descazeaud A, Gas J, Robert G
Service d'urologie, hôpital privé Natecia, Lyon, France.
Service d'urologie, CHU Tours, Tours, France; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Autriche.
Prog Urol. 2021 Apr;31(5):266-274. doi: 10.1016/j.purol.2020.12.001. Epub 2020 Dec 25.
New surgical techniques for the treatment of benign prostatic obstruction (BPO) have emerged in recent years. We sought to give an overview on each of these technologies.
A comprehensive review of the literature between 2013 and 2020 was carried out by a panel of national experts already practicing these interventions. All the data were then discussed among all the co-authors in order to obtain a consensus with regard to the selected articles and their analysis. Finally, an inventory was drawn to provide an overview of these technological advances and their availability in France.
The treatment benign prostatic obstruction has diversified greatly over the past 5 years. 5 new technologies have emerged, allowing today a transurethral non-ablative treatment (UROLIFT®, ITIND®), a transurethral ablative treatment (REZUM®), a transurethral ablative treatment with robotic assistance (AQUABEAM®) or an endovascular management by embolization of the prostatic arteries. Only UROLIFT® is considered an established technology in the latest EAU-Guidelines. The other four are under evaluation and recommendations have only been issued for two of them, AQUABEAM® and the embolization of the prostatic arteries.
These new minimally invasive techniques aim to increase the therapeutic options for the management of BPO in order to offer a management more suited to the wishes of the patient. Some are positioned as an alternative to surgical or medical treatment, others between medical and surgical treatment. These technologies are not all at the same level of development, evaluation and level of proof, but have in common a limited distribution in France, in particular given their cost. Validated studies will allow them to position their subsequent use more precisely.
近年来出现了治疗良性前列腺梗阻(BPO)的新手术技术。我们试图对这些技术逐一进行概述。
一组已经在实施这些干预措施的国家专家对2013年至2020年期间的文献进行了全面回顾。然后所有共同作者对所有数据进行了讨论,以便就所选文章及其分析达成共识。最后,编制了一份清单,以概述这些技术进步及其在法国的可获得性。
在过去5年中,良性前列腺梗阻的治疗方法有了很大的多样化。出现了5种新技术,如今可进行经尿道非消融治疗(UROLIFT®、ITIND®)、经尿道消融治疗(REZUM®)、机器人辅助经尿道消融治疗(AQUABEAM®)或通过前列腺动脉栓塞进行血管内治疗。在最新的欧洲泌尿外科学会(EAU)指南中,只有UROLIFT®被视为一项成熟技术。其他四种技术正在评估中,仅对其中两种技术,即AQUABEAM®和前列腺动脉栓塞发布了建议。
这些新的微创技术旨在增加BPO管理的治疗选择,以便提供更符合患者意愿的管理方法。一些技术被定位为手术或药物治疗的替代方案,另一些则介于药物和手术治疗之间。这些技术并非都处于相同的发展、评估和证据水平,但在法国的分布都很有限,特别是考虑到它们的成本。经过验证的研究将使它们能够更精确地定位其后续应用。