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良性前列腺增生患者前列腺动脉栓塞术的临床结果:一项前瞻性临床研究。

Clinical Outcomes of Prostatic Artery Embolization in Patients with Benign Prostatic Hyperplasia: A Prospective Clinical Study.

作者信息

Dogan Kazım, Erbagci Ahmet, Sen Haluk, Kervancioglu Selim, Erturhan Mehmet Sakıp, Seckiner İlker, Bayrak Ömer

机构信息

Department of Urology, LIV Hospital, Gaziantep Turkey.

Department of Urology, Gaziantep University Faculty of Medicine, Gaziantep, Turkey.

出版信息

Turk J Urol. 2022 May;48(3):215-221. doi: 10.5152/tud.2022.22004.

Abstract

OBJECTIVE

To determine the clinical outcomes of prostatic artery embolization applied to patients with Material and methods: The study includes 30 patients diagnosed with benign prostatic hyperplasia in the urology clinic between 2012 and 2016, for whom anesthesia was contraindicated due to advanced age and comorbidities and who underwent prostatic artery embolization. These patients were evaluated before the procedure and in the 1st, 3rd, 6th, and 12th months after the procedure.

RESULTS

The mean prostate volume of the patients was 68 cm3 before the procedure and 45 cm3 12 monthsafter the procedure. A statistically significant decrease was observed (P = .001). The mean prostate-specific antigen value was 4.9 ng/dL before the procedure and 2.8 ng/dL 12 months after the procedure (P = .008). The mean Qmax value was 0 mL/s before the procedure and 12 mL/s 12 months after the procedure (P = .001). The mean international prostatic symptom scores value was 35 before and 16 twelve months after the proce-dure (P = .001). While the international index of erectile function value was 8.25 before the procedure, it was8.46 12 months after the procedure (P = .32). The quality of life index value was measured as 3.02 before theprocedure and 3.09 twelve months after the procedure; a statistically significant difference was determined (P = .027).

CONCLUSION

Prostatic artery embolization, which is a minimally invasive procedure, can be applied as a safe and effective method to patients with benign prostatic hyperplasia who cannot tolerate anesthesia due to advanced age and comorbidities.

摘要

目的

确定前列腺动脉栓塞术应用于良性前列腺增生患者的临床疗效。

材料和方法

本研究纳入了2012年至2016年间在泌尿外科门诊被诊断为良性前列腺增生的30例患者,这些患者因高龄和合并症而存在麻醉禁忌,并接受了前列腺动脉栓塞术。对这些患者在术前以及术后第1、3、6和12个月进行评估。

结果

患者术前平均前列腺体积为68 cm³,术后12个月为45 cm³。观察到有统计学意义的下降(P = .001)。术前平均前列腺特异性抗原值为4.9 ng/dL,术后12个月为2.8 ng/dL(P = .008)。术前平均最大尿流率(Qmax)值为0 mL/s,术后12个月为12 mL/s(P = .001)。术前平均国际前列腺症状评分值为35,术后12个月为16(P = .001)。术前勃起功能国际指数值为8.25,术后12个月为8.46(P = .32)。生活质量指数值术前测量为3.02,术后12个月为3.09;确定有统计学意义的差异(P = .027)。

结论

前列腺动脉栓塞术作为一种微创手术,可作为一种安全有效的方法应用于因高龄和合并症而无法耐受麻醉的良性前列腺增生患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f25e/9730262/0829d53d2749/tju-48-3-215_f001.jpg

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