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牙齿漂白对成年人口腔健康相关生活质量的影响:一项三盲随机临床试验。

Impact of tooth bleaching on oral health-related quality of life in adults: A triple-blind randomised clinical trial.

机构信息

Graduate Program in Dentistry, Federal University of Pelotas (UFPel), Pelotas, RS, Brazil.

School of Dentistry, Federal University of Pelotas (UFPel), Pelotas, RS, Brazil.

出版信息

J Dent. 2021 Feb;105:103564. doi: 10.1016/j.jdent.2020.103564. Epub 2020 Dec 26.

Abstract

OBJECTIVE

To investigate the impact of tooth bleaching on oral health-related quality of life (OHRQoL) in adults using a randomised clinical trial comparing at-home and in-office bleaching.

METHOD

A total of 130 individuals were randomly allocated to two groups (n = 65) according to the type of treatment. At-home treatment was performed using 10 % carbamide peroxide (2 h/day; 3 weeks) and an in-office placebo, while 35 % hydrogen peroxide was used for in-office (1/week; 3 weeks) and an at-home placebo. Colour was assessed using the CIELAB system using a digital spectrophotometer. Objective and subjective colour change was estimated by calculating CIEDE2000 (ΔE00) and shade guide units (ΔSGU), respectively. The OHRQoL was measured using the Brazilian version of the Oral Health Impact Profile (OHIP-14). All assessments were performed at baseline and after 21 days. For bivariate analysis, the chi-square test, Student's t-test, and Wilcoxon test were used. The effects of OHRQoL were assessed using distribution-based responsiveness.

RESULTS

Objective colour change was observed at home (p = 0.033), in comparison to in-office (p = 0.429). Mean OHIP-14 scores were similar between groups at baseline (p = 0.368) and after treatment (p = 0.695). Bleaching had a moderate positive effect on the OHRQoL of adults, especially with respect to the psychological discomfort domains, social disability, and total OHIP-14 score. The perception of tooth sensitivity in the group that received at-home treatment was negatively associated with OHRQoL (p = 0.037).

CONCLUSION

The bleaching agents were highly effective and demonstrated a moderate influence on the patients' aesthetic perception and psychosocial impact.

摘要

目的

通过比较家庭和诊室漂白的随机临床试验,研究牙齿漂白对成年人口腔健康相关生活质量(OHRQoL)的影响。

方法

根据治疗类型,将 130 名个体随机分为两组(n = 65)。家庭治疗使用 10%的过氧化脲(每天 2 小时;3 周)和诊室安慰剂,而 35%的过氧化氢用于诊室(每周 1 次;3 周)和家庭安慰剂。使用数字分光光度计的 CIELAB 系统评估颜色。通过计算 CIEDE2000(ΔE00)和比色板单位(ΔSGU)分别估计客观和主观颜色变化。使用巴西版口腔健康影响概况(OHIP-14)测量 OHRQoL。所有评估均在基线和 21 天后进行。对于双变量分析,使用卡方检验、学生 t 检验和 Wilcoxon 检验。使用基于分布的响应性评估 OHRQoL 的效果。

结果

与诊室相比,家庭漂白观察到客观颜色变化(p = 0.033)。基线时两组的 OHIP-14 评分相似(p = 0.368),治疗后评分也相似(p = 0.695)。漂白对成年人的 OHRQoL 有中度积极影响,特别是在心理不适、社会障碍和总 OHIP-14 评分方面。接受家庭治疗的组中对牙齿敏感性的感知与 OHRQoL 呈负相关(p = 0.037)。

结论

漂白剂非常有效,对患者的审美感知和心理社会影响有中度影响。

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