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印度南部瑜伽干预对 2 型糖尿病患者生化指标、氧化应激标志物、炎症标志物和睡眠质量的影响:SATYAM 项目的结果。

Effect of yoga intervention on biochemical, oxidative stress markers, inflammatory markers and sleep quality among subjects with type 2 diabetes in South India: Results from the SATYAM project.

机构信息

Department of Diabetology, M.V. Hospital for Diabetes and Prof. M. Viswanathan Diabetes Research Centre (WHO Collaborating Centre for Research Education and Training in Diabetes) (IDF Centre for Excellence in Diabetes Care), Royapuram, Chennai, Tamil Nadu, India.

Department of Yoga, M.V. Hospital for Diabetes and Prof. M. Viswanathan Diabetes Research Centre (WHO Collaborating Centre for Research Education and Training in Diabetes) (IDF Centre for Excellence in Diabetes Care), Royapuram, Chennai, Tamil Nadu, India.

出版信息

Diabetes Res Clin Pract. 2021 Feb;172:108644. doi: 10.1016/j.diabres.2020.108644. Epub 2020 Dec 25.

Abstract

AIMS

The aim of this study was to investigate the effect of yoga intervention on the biochemical, oxidative stress markers and inflammatory markers and sleep quality among subjects with type 2 diabetes.

METHODS

Subjects with type 2 diabetes attending a tertiary care centre for diabetes during Feb 2017 to Oct 2019 in Chennai, India were randomly assigned to two different groups. Group1(non-Yoga) (n = 150) was advised on simple physical exercises whereas group2(Yoga) (n = 150) was trained and advised to do yogasanas with static loosening exercises for 50 min for 5 days in a week. Both the groups were followed up for a period of 3 months. Anthropometric, biochemical, oxidative stress markers, inflammatory markers and sleep quality were assessed at baseline and after follow up.

RESULTS

There was a significant reduction in BMI, blood glucose levels, HbA1c, lipid levels, IL6, TNFα and TBARS in Yoga group as compared to non-Yoga group. There was marked improvement in the levels of Adiponectin, PTGIS and sleep quality among subjects practising yogasanas.

CONCLUSION

Regular practice of yogasanas improved glycaemic control, oxidative stress, inflammatory response and sleep quality among subjects with type 2 diabetes. Hence, Yogasanas can be used as an adjuvant therapy for managing type 2 diabetes.

摘要

目的

本研究旨在探讨瑜伽干预对 2 型糖尿病患者生化指标、氧化应激标志物、炎症标志物和睡眠质量的影响。

方法

2017 年 2 月至 2019 年 10 月期间,印度钦奈的一家三级糖尿病护理中心招募了 2 型糖尿病患者,并将他们随机分配到两个不同的组。第 1 组(非瑜伽组)(n=150)接受简单的体育锻炼建议,而第 2 组(瑜伽组)(n=150)则接受瑜伽体式和静态放松练习的训练和建议,每周 5 天,每天 50 分钟。两组均随访 3 个月。在基线和随访后评估了人体测量学、生化指标、氧化应激标志物、炎症标志物和睡眠质量。

结果

与非瑜伽组相比,瑜伽组的 BMI、血糖水平、HbA1c、血脂水平、IL6、TNFα 和 TBARS 显著降低。练习瑜伽体式的受试者的脂联素、PTGIS 和睡眠质量水平有明显改善。

结论

定期练习瑜伽可以改善 2 型糖尿病患者的血糖控制、氧化应激、炎症反应和睡眠质量。因此,瑜伽可以作为 2 型糖尿病的辅助治疗方法。

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