溴氰菊酯亚急性暴露对乌鳢（Channa argus）的影响：生化指标、抗氧化系统和免疫反应。
Effects of deltamethrin subacute exposure in snakehead fish, Channa argus: Biochemicals, antioxidants and immune responses.
机构信息
College of Animal Science and Technology, Jilin Agriculture University, Changchun 130118, China; Joint Laboratory of Modern Agricultural Technology International Cooperation, Ministry of Education, Jilin Agricultural University, Changchun, Jilin 130118, China; Ministry of Education Laboratory of Animal Production and Quality Security, Jilin Agriculture University, Changchun 130118, China; Jilin Provincial Key Laboratory of Animal Nutrition and Feed Science, Jilin Agricultural University, Changchun 130118, China.
College of Animal Science and Technology, Jilin Agriculture University, Changchun 130118, China.
出版信息
Ecotoxicol Environ Saf. 2021 Feb;209:111821. doi: 10.1016/j.ecoenv.2020.111821. Epub 2020 Dec 24.
To evaluate the effects on biochemicals, antioxidants, immune responses and disease resistance of the snakehead fish, following exposure to deltamethrin at 0.061, 0.121, 0.242, 0.485 and 0.970 μg/L. After 28 d, the biochemical, the levels of antioxidant enzymes and immune enzymes in liver, spleen, kidney and intestine were negatively related to the concentrations of deltamethrin exposure. Likewise, the survival rates of the fish after 7 d challenge with Aeromonas veronii were negatively related. The levels of IL-1β, IL-8, TNF-α, Hsp70 and malondialdehyde in liver, spleen, kidney and intestine were positively connected to the concentrations of deltamethrin exposure. Results demonstrated that environmentally relevant concentrations (0.121, 0.242, 0.485 and 0.970 μg/L) inhibited the biochemicals, antioxidants and immune responses and disease resistance of snakehead fish.
为了评估在 0.061、0.121、0.242、0.485 和 0.970μg/L 浓度的溴氰菊酯暴露下，对生化指标、抗氧化剂、免疫反应和疾病抵抗力的影响。在 28 天后，肝、脾、肾和肠中的生化指标和抗氧化酶、免疫酶水平与溴氰菊酯暴露浓度呈负相关。同样，鱼在 7 天后受到维氏气单胞菌挑战的存活率也呈负相关。肝、脾、肾和肠中的白细胞介素-1β、白细胞介素-8、肿瘤坏死因子-α、热休克蛋白 70 和丙二醛水平与溴氰菊酯暴露浓度呈正相关。结果表明，环境相关浓度（0.121、0.242、0.485 和 0.970μg/L）抑制了蛇头鱼的生化指标、抗氧化剂和免疫反应及疾病抵抗力。
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