Lo Bianco Giuliano, Di Pietro Santi, Mazzuca Emilia, Imburgia Aurelio, Tarantino Luca, Accurso Giuseppe, Benenati Vincenzo, Vernuccio Federica, Bucolo Claudio, Salomone Salvatore, Riolo Marianna
Department of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy.
Anesthesiology and Pain Department, Fondazione Istituto G.Giglio, Cefalù, Italy.
Front Pharmacol. 2020 Dec 9;11:572168. doi: 10.3389/fphar.2020.572168. eCollection 2020.
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2 or COVID-19 disease) was declared a pandemic on 11th March 2020 by the World Health Organization. This unprecedented circumstance has challenged hospitals' response capacity, requiring significant structural and organizational changes to cope with the surge in healthcare demand and to minimize in-hospital risk of transmission. As our knowledge advances, we now understand that COVID-19 is a multi-systemic disease rather than a mere respiratory tract infection, therefore requiring holistic care and expertise from various medical specialties. In fact, the clinical spectrum of presentation ranges from respiratory complaints to gastrointestinal, cardiac or neurological symptoms. In addition, COVID-19 pandemic has created a global burden of mental illness that affects the general population as well as healthcare practitioners. The aim of this manuscript is to provide a comprehensive and multidisciplinary insight into the complexity of this disease, reviewing current scientific evidence on COVID-19 management and treatment across several medical specialties involved in the in-hospital care of these patients.
2020年3月11日,世界卫生组织宣布严重急性呼吸综合征冠状病毒2(SARS-CoV-2或新冠肺炎)为大流行病。这一前所未有的情况对医院的应对能力构成了挑战,需要进行重大的结构和组织变革,以应对医疗需求的激增,并将医院内的传播风险降至最低。随着我们知识的不断进步,我们现在明白,新冠肺炎是一种多系统疾病,而不仅仅是呼吸道感染,因此需要各医学专科提供全面的护理和专业知识。事实上,临床表现的范围从呼吸道症状到胃肠道、心脏或神经症状。此外,新冠肺炎大流行造成了全球精神疾病负担,影响了普通人群以及医护人员。本手稿的目的是对这种疾病的复杂性提供全面和多学科的见解,回顾目前关于这些患者住院治疗所涉及的多个医学专科中新冠肺炎管理和治疗的科学证据。