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一例具有多形性浆母细胞形态的非分泌型浆细胞发育异常的疑难诊断。

A challenging diagnosis of a nonsecretor plasma cell dyscrasia with pleomorphic plasmablastic morphology.

作者信息

Van Landeghem Stijn, Capiau Sara, Bayart Jean-Louis, Vlummens Philip, Van Dorpe Jo, Van Roy Nadine, Philippé Jan

机构信息

Department of Laboratory Medicine Ghent University Hospital Ghent Belgium.

Department of Clinical Hematology Ghent University Hospital Ghent Belgium.

出版信息

Clin Case Rep. 2020 Sep 18;8(12):3070-3074. doi: 10.1002/ccr3.3260. eCollection 2020 Dec.

DOI:10.1002/ccr3.3260
PMID:33363882
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7752493/
Abstract

This report highlights the importance of integrating clinical, radiological, genetic, and pathological laboratory findings to make a correct diagnosis especially with challenging and rare entities.

摘要

本报告强调了整合临床、放射学、遗传学和病理实验室检查结果以做出正确诊断的重要性,尤其是对于具有挑战性的罕见病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce9f/7752493/849d1e64be59/CCR3-8-3070-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce9f/7752493/7bccfee51207/CCR3-8-3070-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce9f/7752493/849d1e64be59/CCR3-8-3070-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce9f/7752493/7bccfee51207/CCR3-8-3070-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce9f/7752493/849d1e64be59/CCR3-8-3070-g002.jpg

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本文引用的文献

1
Aggressive presentation of plasmablastic myeloma.浆母细胞性骨髓瘤的侵袭性表现
BMJ Case Rep. 2020 Apr 6;13(4):e234436. doi: 10.1136/bcr-2020-234436.
2
Translocation (11;14) in newly diagnosed multiple myeloma, time to reclassify this standard risk chromosomal aberration?11 号和 14 号染色体易位在新诊断多发性骨髓瘤中的意义:是否需要重新分类这种标准风险染色体异常?
Eur J Haematol. 2019 Dec;103(6):588-596. doi: 10.1111/ejh.13325. Epub 2019 Oct 6.
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Extraoral plasmablastic lymphomas in a high human immunodeficiency virus endemic area.高发 HIV 流行地区的口腔外 plasmablastic 淋巴瘤。
Histopathology. 2020 Jan;76(2):212-221. doi: 10.1111/his.13964. Epub 2019 Oct 29.
4
Clinical characteristics and prognostic factors of plasmablastic lymphoma patients: analysis of 135 patients from the LYSA group.浆母细胞淋巴瘤患者的临床特征和预后因素:LYSA 研究组 135 例患者的分析。
Ann Oncol. 2017 Apr 1;28(4):843-848. doi: 10.1093/annonc/mdw684.
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Non-secretory multiple myeloma: from biology to clinical management.非分泌型多发性骨髓瘤:从生物学特性到临床管理
Onco Targets Ther. 2016 Dec 15;9:7583-7590. doi: 10.2147/OTT.S122241. eCollection 2016.
6
VTD is superior to VCD prior to intensive therapy in multiple myeloma: results of the prospective IFM2013-04 trial.在强化治疗前,VTD 优于 VCD 治疗多发性骨髓瘤:前瞻性 IFM2013-04 试验结果。
Blood. 2016 May 26;127(21):2569-74. doi: 10.1182/blood-2016-01-693580. Epub 2016 Mar 21.
7
The biology and treatment of plasmablastic lymphoma.浆母细胞淋巴瘤的生物学特性与治疗。
Blood. 2015 Apr 9;125(15):2323-30. doi: 10.1182/blood-2014-10-567479. Epub 2015 Jan 30.
8
Clinicopathologic comparison of plasmablastic lymphoma in HIV-positive, immunocompetent, and posttransplant patients: single-center series of 25 cases and meta-analysis of 277 reported cases.HIV 阳性、免疫功能正常和移植后患者的浆母细胞淋巴瘤的临床病理比较:25 例单中心系列病例和 277 例报道病例的荟萃分析。
Am J Surg Pathol. 2014 Jul;38(7):875-86. doi: 10.1097/PAS.0000000000000234.
9
Management of newly diagnosed symptomatic multiple myeloma: updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus guidelines 2013.新诊断有症状多发性骨髓瘤的治疗:2013 年 Mayo 多发性骨髓瘤分层和风险适应性治疗(mSMART)共识指南更新版。
Mayo Clin Proc. 2013 Apr;88(4):360-76. doi: 10.1016/j.mayocp.2013.01.019.
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