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新生儿期因抗 - c 血型不合所致的溶血性贫血:一例报告

Hemolytic Anemia Due To Anti-c Incompatibility in The Newborn Period: A Case Report.

作者信息

Odabasi Ilkay Ozmeral, Uslu Sinan, Bas Evrim Kiray, Bulbul Ali, Unal Ebru Turkoglu, Acar Duygu Besnili, Tellioglu Ahmet, Ileri Mehmet Fatih

机构信息

Department of Neonatology, Health Sciences University, Sariyer Hamidiye Etfal SUAM, Istanbul, Turkey.

Department of Pediatrics, Health Sciences University, Sariyer Hamidiye Etfal SUAM, Istanbul, Turkey.

出版信息

Sisli Etfal Hastan Tip Bul. 2020 Dec 11;54(4):502-504. doi: 10.14744/SEMB.2019.10693. eCollection 2020.

Abstract

Hemolytic disease of the fetus and newborn is a disease that is caused by maternal alloantibodies to the fetus. In the literature, the frequency of hemolytic disease of the newborn due to Rh (D) sensitization decreased inversely with the increase in the use of anti-D gammaglobulin. However, the importance of minor blood group incompatibilities has increased in the etiology. Clinical presentation in patients with minor blood group incompatibility may vary from subclinical hemolysis findings to active hemolysis and hyperbilirubinemia requiring blood exchange. In this case study, we present a patient with hemolytic anemia due to anti-c antibody incompatibility.

摘要

胎儿和新生儿溶血病是一种由母体针对胎儿的同种抗体引起的疾病。在文献中,由于Rh(D)致敏导致的新生儿溶血病的发生率随着抗D丙种球蛋白使用的增加而呈反比下降。然而,次要血型不相容性在病因学中的重要性有所增加。次要血型不相容患者的临床表现可能从亚临床溶血表现到需要换血的活动性溶血和高胆红素血症不等。在本病例研究中,我们报告了一名因抗-c抗体不相容导致溶血性贫血的患者。

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