Nisell H, Lunell N O, Linde B
Department of Obstetrics and Gynecology, Huddinge University Hospital, Sweden.
Obstet Gynecol. 1988 Feb;71(2):163-6.
Twenty-one subjects with pregnancy-induced hypertension were investigated with regard to the relationship between maternal hemodynamics and fetal growth. Five of the infants were small for gestational age (SGA) (less than tenth percentile) and 16 were appropriate for gestational age (AGA) (greater than tenth percentile). Mean arterial blood pressure, cardiac output, and stroke volume were significantly lower in the group of mothers with SGA infants than in the group with AGA infants (102 +/- 3 versus 115 +/- 3 mmHg, 5.8 +/- 0.2 versus 8.2 +/- 0.3 L/minute, and 76 +/- 7 versus 100 +/- 5 mL, respectively). The results of this investigation suggest that the hemodynamic background to the blood pressure increase in pregnancy-induced hypertension ranges from a low cardiac output, high vascular resistance condition to a high-output, low-normal resistance variant. The former subtype is often associated with the birth of an SGA infant.
对21例妊娠高血压患者进行了研究，以探讨母体血流动力学与胎儿生长之间的关系。其中5例婴儿为小于胎龄儿（SGA）（低于第十百分位数），16例为适于胎龄儿（AGA）（高于第十百分位数）。与AGA婴儿组相比，SGA婴儿组母亲的平均动脉血压、心输出量和每搏输出量显著降低（分别为102±3 mmHg对115±3 mmHg、5.8±0.2 L/分钟对8.2±0.3 L/分钟、76±7 mL对100±5 mL）。该研究结果表明，妊娠高血压患者血压升高的血流动力学背景范围从低心输出量、高血管阻力状态到高输出量、低正常阻力型。前一种亚型通常与SGA婴儿的出生有关。
