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病理性近视相关脉络膜新生血管的血管荧光造影特征。

Angiofluorographic Characteristics of Choroidal Neovascularization associated with Pathologic Myopia.

机构信息

Emergency Eye Hospital, Bucharest, Romania.

Department of Ophthalmology, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

出版信息

Rom J Ophthalmol. 2020 Oct-Dec;64(4):356-363. doi: 10.22336/rjo.2020.57.

Abstract

To evaluate the incidence of choroidal neovascularization (CNV) in high myopic patients who experienced recent visual loss and to describe the characteristics of CNV that develop as a complication of pathologic myopia and were detected by fluorescein angiography (FA). The fluorescein angiograms of 89 patients with high myopia, who registered a recent decrease of visual acuity were reviewed. The incidence of CNV was evaluated and its angiofluorographic appearance described. 172 eyes of 89 patients (six eyes were excluded for different reasons: anophthalmia, dense cataract, history of retinal detachment surgery) were analyzed. Among 89 patients (63 females, 26 males), in 58 cases (~65%), the angiofluorography revealed the presence of a neovascular membrane, and 8 cases presented bilateral CNV. That made a total of 66 eyes. The majority of CNVs were classic (56%), 20% had an occult pattern and 24% were cicatricial. The location was predominantly subfoveal. Considering that the main cause for visual loss in myopic patients is the new-onset myopic CNV, fluorescein angiography should be performed in cases with recent visual loss. When CNV is suspected, FA can demonstrate the presence of myopic CNV, bringing information regarding the type, area, and activity of the CNV and helping exclude other disorders. Due to its location, predominantly sub- or juxtafoveal and to the extended retinal lesions associated with pathologic myopia, the visual prognosis of these patients is poor despite new active treatments.

摘要

评估近期视力下降的高度近视患者中脉络膜新生血管(CNV)的发生率,并描述通过荧光素血管造影(FA)发现的病理性近视并发症中 CNV 的特征。对 89 例因近期视力下降而就诊的高度近视患者的荧光素血管造影进行回顾性分析。评估 CNV 的发生率,并描述其血管造影表现。共分析了 89 例患者(63 名女性,26 名男性)的 172 只眼(因各种原因排除了 6 只眼:无眼球、致密性白内障、视网膜脱离手术史)。在 89 例患者(63 名女性,26 名男性)中,58 例(~65%)的血管造影显示存在新生血管膜,8 例存在双侧 CNV,共 66 只眼。大多数 CNV 为经典型(56%),20%为隐匿型,24%为瘢痕型。位置主要位于黄斑下。考虑到近视患者视力下降的主要原因是新出现的近视性 CNV,因此对于近期视力下降的患者应进行荧光素血管造影。当怀疑存在 CNV 时,FA 可以显示出近视性 CNV 的存在,提供有关 CNV 的类型、面积和活动的信息,并有助于排除其他疾病。由于其位置主要位于黄斑下或黄斑旁,以及与病理性近视相关的广泛视网膜病变,这些患者的视力预后较差,尽管有新的积极治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3295/7739027/b0e483e9e2c1/RomJOphthalmol-64-356-g001.jpg

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