Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan.
Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan
Br J Ophthalmol. 2019 Apr;103(4):457-462. doi: 10.1136/bjophthalmol-2018-312015. Epub 2018 May 23.
To determine the connection between myopic choroidal neovascularisations (CNVs) and intrascleral vessels examined by swept-source optical coherence tomography (OCT).
The data of 124 eyes of 112 consecutive patients with myopic CNVs were retrospectively analysed. A myopic CNV was defined as a CNV occurring in eyes with pathologic myopia based on the META-PM study classification. The images obtained by swept-source OCT were analysed to determine the relationship between perforating scleral vessels and CNVs. The continuity of the scleral vessels and the CNV was also analysed. The OCT angiographic (OCTA) characteristics of the myopic CNVs at the active, scar and atrophic phases were also analysed.
OCTA images showed that CNVs had blood flow in the active, scar and atrophic phases. Scleral perforating vessels were detected just below or around the CNV in 93 eyes (75%). In 10 of the 93 eyes, the scleral vessels and CNV appeared to be continuous through a defect of Bruch's membrane in the OCT images. Indocyanine green angiography showed that these perforating vessels were intrascleral arteries originating from the short posterior ciliary arteries (SPCAs).
Swept-source OCT showed that some of the myopic CNVs were continuous with scleral vessels mainly the SPCA. Further studies to confirm angiographical continuity between these two components are necessary.
探讨通过扫频源光学相干断层扫描（OCT）观察到的近视脉络膜新生血管（CNV）与巩膜内血管之间的关系。
回顾性分析 112 例 124 只眼近视 CNV 患者的资料。根据 META-PM 研究分类，将近视 CNV 定义为发生在病理性近视眼中的 CNV。通过扫频源 OCT 分析图像，以确定穿透性巩膜血管与 CNV 之间的关系。还分析了巩膜血管与 CNV 的连续性。分析活跃期、瘢痕期和萎缩期近视 CNV 的 OCT 血管造影（OCTA）特征。
OCTA 图像显示 CNV 在活跃期、瘢痕期和萎缩期均有血流。在 93 只眼（75%）中，OCT 图像显示 CNV 下方或周围可见巩膜穿透血管。在这 93 只眼中的 10 只眼中，巩膜血管和 CNV 似乎通过 OCT 图像中布鲁赫膜的缺陷连续。吲哚青绿血管造影显示，这些穿透血管是发自睫状后短动脉（SPCA）的巩膜内动脉。
扫频源 OCT 显示，一些近视 CNV 与巩膜血管（主要是 SPCA）连续。需要进一步的研究来证实这两个成分之间的血管连续性。
