El Kawkgi Omar M, Li Dingfeng, Kotwal Anupam, Wermers Robert A
Division of Endocrinology, Diabetes and Nutrition, Mayo Clinic, Rochester, MN.
Mayo Clin Proc Innov Qual Outcomes. 2020 Nov 3;4(6):821-825. doi: 10.1016/j.mayocpiqo.2020.07.006. eCollection 2020 Dec.
As immune checkpoint inhibitor drugs are being used in the treatment of some cancers, unusual adverse events are being reported, labeled as immune-related adverse events. Various endocrinopathies related to immune-related adverse events have been described, among which hypoparathyroidism is exceedingly rare. We report a case of hypoparathyroidism induced by immune checkpoint drugs, highlighting the need for awareness of this emerging complication.
随着免疫检查点抑制剂药物被用于某些癌症的治疗,异常不良事件不断被报道,并被标记为免疫相关不良事件。已经描述了各种与免疫相关不良事件有关的内分泌病,其中甲状旁腺功能减退极为罕见。我们报告一例由免疫检查点药物引起的甲状旁腺功能减退病例,强调需要认识到这种新出现的并发症。