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经尿道前列腺切除术(TURP)后行阴茎背神经阻滞对导尿管相关膀胱不适和疼痛影响的随机对照前瞻性研究。

A randomised-controlled, prospective study on the effect of dorsal penile nerve block after TURP on catheter-related bladder discomfort and pain.

机构信息

Department of Urology, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.

Department of Urology, Konya City Hospital, Konya, Turkey.

出版信息

Int J Clin Pract. 2021 May;75(5):e13963. doi: 10.1111/ijcp.13963. Epub 2021 Jan 11.

Abstract

PURPOSE

In the present study, the impact of penile nerve block (PNB) on postoperative pain and Catheter-Related Bladder Discomfort (CRBD) in the transurethral resection of prostate(TURP) patients were evaluated.

METHODS

Participants of the present study were selected from patients who performed TURP under spinal anaesthesia for benign prostatic hyperplasia (BPH) between January 2018 and July 2020. The present study was planned as a single-centre, randomised-controlled prospective study in which the patients were divided into two groups. Group 1 was administered Control (n:40), and Group 2 ultrasonography(USG) guided PNB (n:40). The patients were included in the Groups, respectively. Visual analogue scale (VAS) scores were questioned and recorded in order to evaluate the postoperative pain complaints of the patients after the operation. In addition, in order to evaluate the CRBD, VAS scores were questioned and recorded as 0th, 0-1th hour, 1st-2nd hour, 2nd-4th hour, 4th-8th hour, 8th-12th hour, and 12th-24th hour. In addition, postoperative pain and need for analgesic drug were recorded. Tramadol was given to patients with moderate to severe CRBD. The findings were compared between the Groups.

RESULTS

There was no statistical difference demographic and per-operative data between Group 1 and Group 2. The CRBD and pain-related VAS scores were significantly higher in Group 1 between the 0 and 8th hours. There was no difference between VAS scores in the postoperative 8-24th hours. In total 24 hours, Group 2's need for tramadol was significantly less than Group 1. On examining the factors affecting CRBD in the multivariate analysis, age, body mass index(BMI), prostate volume, operation time do not affect CRBD statistically, and only PNB reduces CRBD (P: .029). While less drug-related complications were observed in Group 2, no serious complications related to PNB were observed.

CONCLUSION

Penile nerve block is an effective method for the decrease pain and CRBD after urological surgery. It will also reduce the need for analgesics, and provide painless patients in the postoperative period.

摘要

目的

本研究旨在评估阴茎神经阻滞(PNB)对经尿道前列腺切除术(TURP)患者术后疼痛和与导尿管相关的膀胱不适(CRBD)的影响。

方法

本研究的参与者选自 2018 年 1 月至 2020 年 7 月期间因良性前列腺增生(BPH)接受脊髓麻醉下 TURP 的患者。本研究计划为单中心、随机对照前瞻性研究,将患者分为两组。第 1 组给予对照组(n:40),第 2 组给予超声引导 PNB(n:40)。分别将患者纳入两组。为评估患者术后的疼痛主诉,询问并记录视觉模拟评分(VAS)。此外,为评估 CRBD,询问并记录 VAS 评分分别为 0 小时、0-1 小时、1-2 小时、2-4 小时、4-8 小时、8-12 小时和 12-24 小时。此外,记录术后疼痛和需要镇痛药物的情况。给予有中重度 CRBD 的患者曲马多。比较两组之间的结果。

结果

第 1 组和第 2 组在人口统计学和围手术期数据方面无统计学差异。第 1 组在 0-8 小时内的 CRBD 和疼痛相关 VAS 评分明显较高。术后 8-24 小时 VAS 评分无差异。在 24 小时总时间内,第 2 组需要曲马多的次数明显少于第 1 组。在多变量分析中,检查影响 CRBD 的因素时,年龄、体重指数(BMI)、前列腺体积、手术时间对 CRBD 无统计学影响,只有 PNB 可降低 CRBD(P:0.029)。虽然第 2 组观察到较少的药物相关并发症,但未观察到与 PNB 相关的严重并发症。

结论

阴茎神经阻滞是减少泌尿外科手术后疼痛和 CRBD 的有效方法。它还将减少对镇痛药的需求,并为术后患者提供无痛。

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