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经尿道手术后膀胱痉挛不适:术前、术中和术后预测因素的前瞻性观察研究

Bladder Spasm Discomfort After Transurethral Surgery: A Prospective Observational Study of Preoperative, Intraoperative, and Postoperative Predictive Factors.

作者信息

Markopoulos Titos, Katsimperis Stamatios, Lazarou Lazaros, Tzelves Lazaros, Mitsogiannis Iraklis, Papatsoris Athanasios, Skolarikos Andreas, Varkarakis Ioannis

机构信息

Urology, Second Department of Urology, National and Kapodistrian University of Athens, Athens, GRC.

Urology, Second Department of Urology, National and Kapodistrian University of Athens, Sismanogleio General Hospital, Athens, GRC.

出版信息

Cureus. 2025 May 20;17(5):e84508. doi: 10.7759/cureus.84508. eCollection 2025 May.

DOI:10.7759/cureus.84508
PMID:40400652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12092756/
Abstract

Catheter-related bladder discomfort (CRBD) is a common and distressing complication following transurethral urologic procedures such as transurethral resection of the prostate (TURP) and transurethral resection of bladder tumors (TURBT). This prospective observational study investigated the role of preoperative, intraoperative, and postoperative factors in predicting the severity of postoperative bladder spasms. A total of 122 patients were enrolled, and bladder discomfort was assessed using the Visual Analogue Scale (VAS) during their postoperative hospital stay. Most clinical and surgical variables, including anesthesia type, procedure type, catheter type, energy modality, and patient demographics, showed no significant association with bladder discomfort severity. However, catheter balloon volume emerged as a significant predictor, with patients receiving 40 mL balloon volumes reporting higher VAS scores compared to those with smaller volumes (p = 0.003). Additionally, a weak but statistically significant correlation was found between hematocrit drop and VAS scores (rho = 0.18, p = 0.047), suggesting a possible link between intraoperative blood loss and postoperative discomfort. These findings highlight the potential for simple interventions, such as optimizing catheter balloon volume, to alleviate CRBD and enhance postoperative recovery.

摘要

导尿管相关膀胱不适(CRBD)是经尿道泌尿外科手术后常见且令人痛苦的并发症,如经尿道前列腺切除术(TURP)和经尿道膀胱肿瘤切除术(TURBT)。这项前瞻性观察性研究调查了术前、术中和术后因素在预测术后膀胱痉挛严重程度中的作用。共纳入122例患者,并在其术后住院期间使用视觉模拟量表(VAS)评估膀胱不适情况。大多数临床和手术变量,包括麻醉类型、手术类型、导尿管类型、能量模式和患者人口统计学特征,与膀胱不适严重程度均无显著关联。然而,导尿管球囊容量成为一个显著的预测因素,接受40 mL球囊容量的患者报告的VAS评分高于球囊容量较小的患者(p = 0.003)。此外,还发现血细胞比容下降与VAS评分之间存在微弱但具有统计学意义的相关性(rho = 0.18,p = 0.047),这表明术中失血与术后不适之间可能存在联系。这些发现凸显了简单干预措施(如优化导尿管球囊容量)在减轻CRBD和促进术后恢复方面的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/595e/12092756/cc0b04edb23d/cureus-0017-00000084508-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/595e/12092756/2c4d7775034c/cureus-0017-00000084508-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/595e/12092756/cc0b04edb23d/cureus-0017-00000084508-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/595e/12092756/2c4d7775034c/cureus-0017-00000084508-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/595e/12092756/cc0b04edb23d/cureus-0017-00000084508-i02.jpg

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本文引用的文献

1
Incidence and Determinants of Catheter-Related Bladder Spasms Following Transurethral Resection of the Prostate; A Prospective Review of 80 Cases.经尿道前列腺切除术后导管相关膀胱痉挛的发生率及决定因素;80例前瞻性研究
Niger Med J. 2024 Apr 21;65(1):75-80. doi: 10.60787/nmj-v65i1-453. eCollection 2024 Jan-Feb.
2
Effect of Pudendal Nerve Block on the Prevention of Postoperative Bladder Spasm and Catheter-Related Bladder Discomfort in Male Patients Undergoing Transurethral Holmium Laser Enucleation of the Prostate.阴部神经阻滞对经尿道钬激光前列腺剜除术男性患者术后膀胱痉挛和导尿管相关性膀胱不适的预防作用。
Clin Interv Aging. 2022 Nov 30;17:1729-1738. doi: 10.2147/CIA.S384612. eCollection 2022.
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The Effect of Transcutaneous Electrical Acupoint Stimulation on Postoperative Catheter-Related Bladder Discomfort in Patients Undergoing Transurethral Resection of the Prostate.
经皮穴位电刺激对行经尿道前列腺切除术患者术后导管相关膀胱不适的影响
Evid Based Complement Alternat Med. 2021 Feb 4;2021:6691459. doi: 10.1155/2021/6691459. eCollection 2021.
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Efficacy and Safety Evaluation of Transurethral Resection of the Prostate versus Plasmakinetic Enucleation of the Prostate in the Treatment of Massive Benign Prostatic Hyperplasia.经尿道前列腺切除术与等离子前列腺剜除术治疗巨大良性前列腺增生的疗效和安全性评价。
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A randomised-controlled, prospective study on the effect of dorsal penile nerve block after TURP on catheter-related bladder discomfort and pain.经尿道前列腺切除术(TURP)后行阴茎背神经阻滞对导尿管相关膀胱不适和疼痛影响的随机对照前瞻性研究。
Int J Clin Pract. 2021 May;75(5):e13963. doi: 10.1111/ijcp.13963. Epub 2021 Jan 11.
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Exp Ther Med. 2021 Jan;21(1):47. doi: 10.3892/etm.2020.9478. Epub 2020 Nov 18.
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J Clin Med. 2019 May 29;8(6):759. doi: 10.3390/jcm8060759.
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Evaluation of pain and catheter-related bladder discomfort relative to balloon volumes of indwelling urinary catheters: A prospective study.留置导尿管球囊容积与疼痛及与导管相关的膀胱不适相关性评估:一项前瞻性研究。
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