Department of Internal Medicine, Maastricht University Medical Center & Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands.
J Clin Hypertens (Greenwich). 2021 Feb;23(2):201-207. doi: 10.1111/jch.14117. Epub 2020 Dec 27.
The aldosterone-to-renin ratio (ARR) is a common screening test for primary aldosteronism in hypertensives. However, there are many factors which could confound the ARR test result and reduce the accuracy of this test. The present review's objective is to identify these factors and to describe to what extent they affect the ARR. Our analysis revealed that sex, age, posture, and sodium-intake influence the ARR, whereas assay techniques do not. Race and body mass index have an uncertain effect on the ARR. We conclude that several factors can affect the ARR. Not taking these factors into account could lead to misinterpretation of the ARR.
醛固酮与肾素比值（ARR）是高血压患者原发性醛固酮增多症的常用筛查试验。然而，有许多因素可能会干扰 ARR 检测结果，降低该检测的准确性。本综述的目的是确定这些因素，并描述它们在多大程度上影响 ARR。我们的分析表明，性别、年龄、体位和钠摄入量会影响 ARR，而检测技术则不会。种族和体重指数对 ARR 的影响不确定。我们得出结论，有几个因素会影响 ARR。不考虑这些因素可能会导致对 ARR 的错误解读。
