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哥伦比亚由环境霉菌半裸新座壳引起的甲癣及体外抗真菌药敏评估

Onychomycosis caused by the environmental mold Neoscytalidium dimidiatum in Colombia, and in vitro antifungal susceptibility evaluation.

作者信息

Gil-González Manuela, Gómez-Velásquez Juan C, Loaiza-Díaz Natalia, Florez-Muñoz Sindy V, Hernández-Herrera Gilma N, Mesa-Arango Ana Cecilia

机构信息

Grupo de Investigación Dermatológica, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.

Synlab Colombia S.A.S, Medellín, Colombia.

出版信息

Med Mycol. 2020 Dec 28. doi: 10.1093/mmy/myaa105.

Abstract

UNLABELLED

Neoscytalidium dimidiatum is a plant pathogen, but can also cause onychomycosis. We compared clinical and epidemiological data of cases of onychomycosis caused by N. dimidiatum and Trichophyton rubrum. We also evaluated the in vitro antifungal susceptibility of N. dimidiatum clinical isolates. It was not possible to establish any statistical differences between groups, except the place of residence and the number of affected nails. The results suggest that onychomycosis caused by N. dimidiatum is clinically similar to that caused by T. rubrum; besides, N. dimidiatum has been shown to have low sensitivity to itraconazole, but high to terbinafine.

LAY SUMMARY

Cases of onychomycosis caused by Neoscytalidium dimidiatum were studied and compared to cases of onychomycosis caused by T. rubrum. The individuals affected were adults, and the clinical characteristics were not different between groups; accordingly, mycological diagnosis is mandatory.

摘要

未标注

新暗色柱节孢是一种植物病原体,但也可引起甲癣。我们比较了由新暗色柱节孢和红色毛癣菌引起的甲癣病例的临床和流行病学数据。我们还评估了新暗色柱节孢临床分离株的体外抗真菌药敏性。除居住地和患甲数量外,无法在两组之间建立任何统计学差异。结果表明,新暗色柱节孢引起的甲癣在临床上与红色毛癣菌引起的甲癣相似;此外,已表明新暗色柱节孢对伊曲康唑敏感性低,但对特比萘芬敏感性高。

简要概述

对由新暗色柱节孢引起的甲癣病例进行了研究,并与由红色毛癣菌引起的甲癣病例进行了比较。受影响的个体为成年人,两组之间的临床特征无差异;因此,真菌学诊断是必需的。

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