Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Medicine (Baltimore). 2020 Dec 18;99(51):e23754. doi: 10.1097/MD.0000000000023754.
Insomnia with high incidence is usually accompanied by many other diseases, especially mental disorders with the under-diagnosis and under-treatment. Some studies demonstrated that acupuncture may be effective for emotional disorders accompanied by insomnia. The systematic review protocol is designed to guiding analysis the effectiveness and safety of acupuncture for emotional disorders in patients with insomnia.
Seven databases, Cochrane central register of controlled trials, Medline, Embase, China National Knowledge Infrastructure, Chinese Biomedical Literature database, VIP database and Wanfang database, will be searched from initial to December 2020. Randomized controlled trials (RCTs) of acupuncture for insomnia with emotional disorders (depression and anxiety) outcomes, which were reported in Chinese or English, will be included. The primary outcome is the change of degree of anxiety and depression. Study selection, data extraction and assessment of the risk of bias will be performed independently by 2 or more reviewers. Available data will be synthesized and statistically analyzed in RevMan V.5.3. The model of fixed effects will be used for the pooled data when the heterogeneity tests show little or no statistical heterogeneity (I2 < 50%). The random-effects model will be taken with heterogeneous data (50% ≤ I2 < 75%).
The effect of acupuncture on emotional disorders in patients with insomnia will be assessed on Hamilton anxiety Scale, Hamilton anxiety Scale, Pittsburgh Sleep Quality Index, Insomnia Severity Index, Self-rating Anxiety Scale, Self-rating Depressive Scale and the number of participants secede and the number of patients reported adverse events.
the emotional disorders interaction with insomnia and the increase of risk on disease evolving and insomnia-related burden, it is so momentous to know that the role of insomnia treatment on comorbidities. We should concern about the management of emotional disorders when treat insomnia, and acupuncture treatment anxiety and depression caused by insomnia may be effective.
Ethics approval is not be needed because the data will not contain individual patient data, and there are no concerns about privacy. The results of this meta-analysis will be disseminated through publication in a peer-reviewed academic journal or relevant conference.
INPLASY2020100115.
发病率较高的失眠常伴有许多其他疾病，尤其是精神障碍，其漏诊和治疗不足。一些研究表明，针灸可能对伴有失眠的情绪障碍有效。本系统评价方案旨在指导分析针灸治疗失眠伴情绪障碍（抑郁和焦虑）的有效性和安全性。
从初始到 2020 年 12 月，我们将检索七个数据库，包括 Cochrane 对照试验中心注册库、Medline、Embase、中国知网、中国生物医学文献数据库、维普数据库和万方数据库。纳入针灸治疗失眠伴情绪障碍（抑郁和焦虑）结局的随机对照试验（RCT），无论发表语言如何。主要结局是焦虑和抑郁程度的变化。研究选择、数据提取和偏倚风险评估将由 2 名或以上评审员独立进行。可用数据将用 RevMan V.5.3 进行综合和统计分析。当异质性检验显示统计异质性很小或没有（I2 < 50%）时，将采用固定效应模型对汇总数据进行合并。当存在异质性数据（50% ≤ I2 < 75%）时，将采用随机效应模型。
将使用汉密尔顿焦虑量表、汉密尔顿焦虑量表、匹兹堡睡眠质量指数、失眠严重程度指数、自评焦虑量表、自评抑郁量表和退出人数以及报告不良事件的患者人数来评估针灸对失眠患者情绪障碍的影响。
情绪障碍与失眠相互作用，增加疾病进展和与失眠相关负担的风险，因此了解失眠治疗对合并症的作用至关重要。我们在治疗失眠时应关注情绪障碍的管理，针灸治疗失眠引起的焦虑和抑郁可能是有效的。
由于数据不包含个体患者数据，也不存在隐私问题，因此不需要伦理批准。本荟萃分析的结果将通过发表在同行评议的学术期刊或相关会议上进行传播。
INPLASY 注册号：INPLASY2020100115。
