Elmagzoub Wisal A, Adam Nabawia M, Idris Sanaa M, Mukhtar Mohamed E, Abdelaziz Sanaa A, Okuni Julius B, Ojok Lonzy, Abd El Wahed Ahmed, Eltayeb ElSagad, Gameel Ahmed A, Eltom Kamal H
Unit of Animal Health and Safety of Animal Products, Institute for Studies and Promotion of Animal Exports, University of Khartoum, Shambat 13314, Khartoum North, Sudan.
Department of Biology and Biotechnology, College of Applied and Industrial Sciences, University of Bahri, Alkadaro 13316, Khartoum North, Sudan.
Vet Sci. 2020 Dec 21;7(4):209. doi: 10.3390/vetsci7040209.
Paratuberculosis, caused by subspecies (MAP), is a chronic wasting disease mainly of domestic and wild ruminants. It occurs worldwide, causing significant economic losses through decreased productivity, low fertility, increased cull rates and mortality. It is listed by the OIE (World Organization for Animal Health) as a disease of concern to trade in animals. Prevalence of this disease can be studied by detecting anti-MAP antibodies by Enzyme linked immunosorbent Assay (ELISA). The aim of this study was to investigate the current prevalence of MAP infection in cattle in Khartoum State. The overall apparent prevalence of MAP infection was found to be 6.3% and 18.9% at animal and herd levels, respectively. All seropositive animals were cross-bred females of good body condition; most of them (>90%) were >3 years old and >50% were from medium-sized herds in Omdurman. No significant association ( > 0.05) was found between seropositivity and animal herd size. The prevalence of MAP infection in Khartoum State is still low to medium compared to other parts of the world, but it is comparable to those reported from other African countries. Further studies with the view of designing nationwide surveys in domestic ruminants and camels in other states of the country are needed for establishing control programmes.
副结核病由副结核分枝杆菌亚种（MAP）引起，是一种主要影响家养和野生反刍动物的慢性消耗性疾病。该病在全球范围内均有发生，通过降低生产力、降低繁殖力、提高淘汰率和死亡率造成重大经济损失。它被世界动物卫生组织（OIE）列为影响动物贸易的关注疾病。可通过酶联免疫吸附测定（ELISA）检测抗MAP抗体来研究这种疾病的流行情况。本研究的目的是调查喀土穆州牛群中MAP感染的当前流行情况。结果发现，在个体动物和畜群水平上，MAP感染的总体表观流行率分别为6.3%和18.9%。所有血清阳性动物均为身体状况良好的杂交雌性；其中大多数（>90%）年龄>3岁，>50%来自恩图曼的中型畜群。血清阳性与动物畜群规模之间未发现显著关联（>0.05）。与世界其他地区相比，喀土穆州MAP感染的流行率仍处于低至中等水平，但与其他非洲国家报告的水平相当。为制定控制计划，需要进一步开展研究，以便在该国其他州对家养反刍动物和骆驼进行全国性调查。
