Feanny S, Forsyth S, Corey M, Levison H, Zimmerman B
Division of Allergy, Hospital for Sick Children, Toronto, Canada.
Ann Allergy. 1988 Jan;60(1):64-8.
One hundred and seventeen patients with cystic fibrosis (CF) were evaluated for criteria suggestive of allergic bronchopulmonary aspergillosis (ABPA) and atopy. We found positive skin tests to Aspergillus to be more common in patients with CF than comparison groups with asthma or non-specific nasal symptoms. This increased prick skin test reactivity to Aspergillus was especially noticeable in a group of CF patients having only one or two skin tests positive, preponderantly Aspergillus. Twelve of the CF patients (10%) had further immunologic criteria suggestive of ABPA. These patients had significantly worse lung function than the CF patients without such criteria.
对117例囊性纤维化（CF）患者进行了评估，以确定是否存在提示变应性支气管肺曲霉菌病（ABPA）和特应性的标准。我们发现，CF患者中对曲霉菌的皮肤试验阳性比哮喘或非特异性鼻部症状的对照组更为常见。这种对曲霉菌针刺皮肤试验反应性的增加在一组仅一两个皮肤试验呈阳性（主要是对曲霉菌）的CF患者中尤为明显。12例CF患者（10%）有进一步提示ABPA的免疫学标准。这些患者的肺功能明显比无此类标准的CF患者差。
