Infectious Disease Surveillance Center, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo, 162-8640, Japan.
Victorian Infectious Diseases Reference Laboratory, At the Peter Doherty Institute for Infection and Immunity, 792 Elizabeth St, Melbourne, VIC, 3004, Australia.
J Infect Chemother. 2021 May;27(5):684-689. doi: 10.1016/j.jiac.2020.12.003. Epub 2020 Dec 26.
Elimination of measles and rubella has been achieved in several countries and some regions. After verified measles elimination, some countries have reported outbreaks among adults in occupational settings such as health care institution and school setting. Studies have reported that knowledge and attitude for measles and/or rubella are significantly associated with immunization uptake in adults, but few studies have been conducted in settings other than health care facilities and schools.
We conducted a cross-sectional study among 134 office employees during a routine health checkup in June 17-20, 2014, to examine the association between willingness to receive immunization and knowledge and attitudes.
Approximately 75% had a protective level of antibody for measles (PA≥1:256) and rubella (HI ≥ 32 IU/mL). After adjustment for sex, age and immune status, the attitudes that immunization prevents measles (adjusted odds ratio [aOR] = 7.8, 95% confidence interval [95%CI]: 2.5-24.7) and prevents infection and transmission to others (aOR = 4.0, 95%CI: 1.4-11.4). Knowing that males are the vulnerable group for rubella infection (aOR = 5.8, 95%CI: 2.4-13.9), attitude that immunization prevents rubella infection (aOR = 7.9, 95%CI: 2.4-26.5), and prevents infection and transmit to others (aOR = 6.7, 95%CI: 2.2-20.1) were significantly associated with willingness to receive immunization after adjustment for sex, age, and immune status.
Studies have shown that physicians and other health care workers are important source of information for promotion of immunization. Thus, we recommend that physicians educate and promote immunization for measles and/or rubella to adults working in offices during routine health checks.
在一些国家和地区已经实现了麻疹和风疹的消除。在验证麻疹消除后，一些国家报告了在医疗机构和学校等职业环境中成年人的暴发。研究表明，麻疹和/或风疹的知识和态度与成年人的免疫接种率显著相关，但在除医疗机构和学校以外的环境中进行的研究较少。
我们在 2014 年 6 月 17 日至 20 日期间对 134 名办公室员工进行了横断面研究，以检查接种意愿与知识和态度之间的关系。
约 75%的人具有麻疹（PA≥1：256）和风疹（HI≥32 IU/ml）的保护性抗体水平。在调整性别、年龄和免疫状态后，接种疫苗可预防麻疹（调整后的优势比[aOR] = 7.8，95%置信区间[95%CI]：2.5-24.7）和预防感染及传播给他人（aOR = 4.0，95%CI：1.4-11.4）的态度。知道男性是风疹感染的易感染群体（aOR = 5.8，95%CI：2.4-13.9），接种疫苗可预防风疹感染（aOR = 7.9，95%CI：2.4-26.5），以及预防感染和传播给他人（aOR = 6.7，95%CI：2.2-20.1）的态度在调整性别、年龄和免疫状态后与接种意愿显著相关。
研究表明，医生和其他卫生保健工作者是促进免疫接种的重要信息来源。因此，我们建议医生在常规健康检查期间向在办公室工作的成年人宣传麻疹和/或风疹的免疫接种。
