Quigley Karen S, Kanoski Scott, Grill Warren M, Barrett Lisa Feldman, Tsakiris Manos
Department of Psychology, Northeastern University, Boston, MA, USA; Edith Nourse Rogers Memorial VA Hospital, Bedford, MA, USA.
Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA.
Trends Neurosci. 2021 Jan;44(1):29-38. doi: 10.1016/j.tins.2020.09.008.
We review recent work on the functions of interoceptive processing, by which the nervous system anticipates, senses, and integrates signals originating from the body. We focus on several exemplar functions of interoception, including energy regulation (ingestion and excretion), memory, affective and emotional experience, and the psychological sense of self. We emphasize two themes across these functions. First, the anatomy of interoceptive afferents makes it difficult to manipulate or directly measure interoceptive signaling in humans. Second, recent evidence shows that multimodal integration occurs across interoceptive modalities and between interoceptive and exteroceptive modalities. Whereas exteroceptive multimodal integration has been studied relatively extensively, fundamental questions remain regarding multimodal integration that involves interoceptive modalities. Future empirical work is required to better understand how and where multimodal interoceptive integration occurs.
我们回顾了近期关于内感受处理功能的研究，通过该功能，神经系统对源自身体的信号进行预测、感知和整合。我们聚焦于内感受的几个典型功能，包括能量调节（摄入和排泄）、记忆、情感和情绪体验以及自我的心理感受。我们强调贯穿这些功能的两个主题。第一，内感受传入神经的解剖结构使得在人类中操纵或直接测量内感受信号变得困难。第二，最近的证据表明，多模态整合发生在内感受模态之间以及内感受和外感受模态之间。虽然外感受多模态整合已经得到了相对广泛的研究，但关于涉及内感受模态的多模态整合仍存在基本问题。未来需要进行实证研究，以更好地理解多模态内感受整合是如何发生以及发生在何处。
