Chenevart P, Gloor E
Schweiz Med Wochenschr. 1980 Apr 5;110(14):531-9.
The present study analyzes the anatomical and clinical elements in 53 cases of low potential malignant ovarian tumors (24 serous and 29 mucinous) from the biopsies of our Institute collected during the period 1966 to 1976. 17 serous tumors were stage I, 2 stage IIB, 3 stage III and 2 stage IV. All the mucinous tumors were stage I. 4 cases exhibited ascites. A third of the serous tumors were bilateral, while all the mucinous tumors were unilateral. Treatment in all cases was excision of the tumor with or without hysterectomy. In 12 cases complementary chemotherapy was given. Follow-up studies were performed only in 36 of the 53 cases and showed that no patient died of her tumor. This illustrates well the low malignant potential of this type of tumor even when discovered at an advanced stage. The diagnosis is histological and based on precise criteria requiring wide microscopic sampling. Experience shows that differentiation between borderline tumors and carcinoma is more difficult in mucinous than in serous tumors. Due to the particular classification of these tumors, which could lead to confusion, the diagnostic formulation must be absolutely accurate if it is to be understood clearly by the physician.
本研究分析了1966年至1976年期间我院活检的53例低恶性潜能卵巢肿瘤(24例浆液性和29例黏液性)的解剖学和临床因素。17例浆液性肿瘤为Ⅰ期,2例为ⅡB期,3例为Ⅲ期,2例为Ⅳ期。所有黏液性肿瘤均为Ⅰ期。4例出现腹水。三分之一的浆液性肿瘤为双侧性,而所有黏液性肿瘤均为单侧性。所有病例均采用肿瘤切除治疗,可选择或不选择子宫切除术。12例接受了辅助化疗。仅对53例中的36例进行了随访研究,结果显示无患者死于肿瘤。这充分说明了即使在晚期发现,这类肿瘤的恶性潜能也较低。诊断依靠组织学检查,基于精确的标准,需要广泛的显微镜下取材。经验表明,黏液性肿瘤中交界性肿瘤与癌的鉴别比浆液性肿瘤更困难。由于这些肿瘤的特殊分类可能导致混淆,诊断表述必须绝对准确,以便医生能清楚理解。