Hahn R C, Petitti D B
Department of Mental Health, Kaiser Permanente Medical Center, Walnut Creek, CA 94596.
Cancer. 1988 Feb 15;61(4):845-8. doi: 10.1002/1097-0142(19880215)61:4<845::aid-cncr2820610434>3.0.co;2-q.
Using data from the Walnut Creek Contraceptive Drug Study (a prospective study begun in 1969 and continuing to the present), Minnesota Multiphasic Personality Inventory-(MMPI) measured scores for depression of 8932 women were studied in relation to the incidence of breast cancer. No statistically significant association between MMPI scores for depression and the subsequent development of breast cancer was found. There was neither an association of risk of breast cancer with repression/sensitization as measured on the MMPI nor with scores on the MMPI lie scale. This study is unique because it represents the largest reported prospective cohort in which the association between depression and breast cancer development has been examined.
利用核桃溪避孕药物研究（一项始于1969年并持续至今的前瞻性研究）的数据，对8932名女性的明尼苏达多相人格调查表（MMPI）抑郁测量得分与乳腺癌发病率之间的关系进行了研究。未发现MMPI抑郁得分与随后乳腺癌的发生之间存在统计学上的显著关联。乳腺癌风险与MMPI测量的压抑/敏感化以及MMPI说谎量表得分均无关联。这项研究具有独特性，因为它是已报道的最大规模的前瞻性队列研究，其中对抑郁与乳腺癌发展之间的关联进行了检验。
