作物类胡萝卜素的 CRISPR 时代生物强化。
Carotenoid Biofortification of Crops in the CRISPR Era.
机构信息
King Abdullah University of Science and Technology (KAUST), Division of Biological and Environmental Science and Engineering, Center for Desert Agriculture, the BioActives Laboratory, Thuwal 23955-6900, Saudi Arabia.
King Abdullah University of Science and Technology (KAUST), Division of Biological and Environmental Science and Engineering, Center for Desert Agriculture, the BioActives Laboratory, Thuwal 23955-6900, Saudi Arabia.
出版信息
Trends Biotechnol. 2021 Sep;39(9):857-860. doi: 10.1016/j.tibtech.2020.12.003. Epub 2020 Dec 29.
Carotenoids are micronutrients important for human health. The continuous improvements in clustered regularly interspaced short palindromic repeats (CRISPR)-based genome-editing techniques make rapid, DNA/transgene-free and targeted multiplex genetic modification a reality, thus promising to accelerate the breeding and generation of 'golden' staple crops. We discuss here the progress and future prospects of CRISPR/Cas9 applications for carotenoid biofortification.
类胡萝卜素是对人类健康很重要的微量营养素。基于簇状规律间隔短回文重复序列（CRISPR）的基因组编辑技术的不断改进，使得快速、无 DNA/转基因和靶向的多重遗传修饰成为现实，从而有望加速“金色”主要农作物的培育和产生。我们在这里讨论了 CRISPR/Cas9 应用于类胡萝卜素生物强化的进展和未来前景。
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