Clinical Pharmacy Unit and Research Team, Department of Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Amhara, Ethiopia
Pharmacology Unit and Research Team, Department of Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Amhara, Ethiopia.
BMJ Open. 2020 Dec 31;10(12):e040238. doi: 10.1136/bmjopen-2020-040238.
This study aimed to assess the clinical pattern and predictors of stroke treatment outcomes among hospitalised patients in Felege Hiwot comprehensive specialised hospital (FHCSH) in northwest Ethiopia.
A retrospective cross-sectional study.
The study was conducted medical ward of FHCSH.
The medical records of 597 adult patients who had a stroke were included in the study. All adult (≥18 years) patients who had a stroke had been admitted to the medical ward of FHSCH during 2015-2019 were included in the study. However, patients with incomplete medical records (ie, incomplete treatment regimen and the status of the patients after treatment) were excluded in the study.
In the present study, 317 (53.1%) were males, and the mean age of the study participants was 61.08±13.76 years. About two-thirds of patients (392, 65.7%) were diagnosed with ischaemic stroke. Regarding clinical pattern, about 203 (34.0%) of patients complained of right-side body weakness and the major comorbid condition identified was hypertension (216, 64.9%). Overall, 276 (46.2%) of them had poor treatment outcomes, and 101 (16.9%) of them died. Patients who cannot read and write (AOR=42.89, 95% CI 13.23 to 111.28, p<0.001), attend primary school (AOR=22.11, 95% CI 6.98 to 55.99, p<0.001) and secondary school (AOR=4.20, 95% CI 1.42 to 12.51, p<0.001), diagnosed with haemorrhagic stroke (AOR=2.68, 95% CI 1.62 to 4.43, p<0.001) and delayed hospital arrival more than 24 hours (AOR=2.92, 95% CI 1.83 to 4.66, p=0.001) were the independent predictors of poor treatment outcome.
Approximately half of the patients who had a stroke had poor treatment outcomes. Ischaemic stroke was the most predominantly diagnosed stroke type. Education status, types of stroke and the median time from onset of symptoms to hospitalisation were the predictors of treatment outcome. Health education should be given to patients regarding clinical symptoms of stroke. In addition, local healthcare providers need to consider the above risk factors while managing stroke.
本研究旨在评估埃塞俄比亚西北部费莱吉洪综合专科医院（FHCSH）住院患者中风治疗结果的临床模式和预测因素。
回顾性横断面研究。
研究在 FHCSH 的内科病房进行。
本研究纳入了 2015 年至 2019 年期间在 FHCSH 内科住院的 597 名成年中风患者的病历。所有（≥18 岁）在 FHCSH 内科住院的成年中风患者均纳入本研究。然而，在研究中排除了病历不完整的患者（即，治疗方案不完整以及治疗后患者的状况）。
在本研究中，317 名（53.1%）为男性，研究参与者的平均年龄为 61.08±13.76 岁。大约三分之二的患者（392 名，65.7%）被诊断为缺血性中风。关于临床模式，约 203 名（34.0%）患者抱怨右侧身体无力，主要的合并症是高血压（216 名，64.9%）。总体而言，276 名（46.2%）患者治疗效果不佳，101 名（16.9%）患者死亡。无法读写的患者（AOR=42.89，95%CI 13.23 至 111.28，p<0.001）、小学（AOR=22.11，95%CI 6.98 至 55.99，p<0.001）和中学（AOR=4.20，95%CI 1.42 至 12.51，p<0.001）、诊断为出血性中风（AOR=2.68，95%CI 1.62 至 4.43，p<0.001）和发病后 24 小时以上到达医院（AOR=2.92，95%CI 1.83 至 4.66，p=0.001）是治疗结果不良的独立预测因素。
大约一半的中风患者治疗效果不佳。缺血性中风是最主要的诊断类型。教育程度、中风类型和发病到住院的中位数时间是治疗结果的预测因素。应向患者提供有关中风临床症状的健康教育。此外，当地医疗保健提供者在管理中风时需要考虑上述危险因素。
