血小板减少症：川崎病的一种并发症。

Thrombocytopenia: a complication of Kawasaki disease.

作者信息

Hara T, Mizuno Y, Akeda H, Fukushige J, Ueda K, Aoki T, Sunagawa H, Honda S, Hijii T, Yamaguchi Y

机构信息

Department of Paediatrics, Faculty of Medicine, Kyushu University, Fukuoka city, Japan.

出版信息

Eur J Pediatr. 1988 Jan;147(1):51-3. doi: 10.1007/BF00442611.

DOI:10.1007/BF00442611

PMID:3338478

Abstract

Thrombocytopenia was observed in 10 (2.0%) of 486 children with Kawasaki disease. In nine of the ten, the minimal platelet count of 94,000 +/- 38,000 (SD)/mm3 was seen on day 6.8 +/- 2.2 (SD) of illness and the platelet counts were elevated to the normal level in 1-2 weeks. Thrombocytopenia in the nine appeared to be caused via coagulation-mediated platelet consumption, while the remaining child was diagnosed as having idiopathic thrombocytopenic purpura. One of the two who had severe coagulation-mediated thrombocytopenia of less than 50,000/mm3 developed coronary aneurysms persisting over 1 year.

摘要

486例川崎病患儿中有10例（2.0%）出现血小板减少。这10例中的9例，在发病6.8±2.2（标准差）天血小板计数降至最低，为94,000±38,000（标准差）/mm³，1 - 2周内血小板计数升至正常水平。这9例血小板减少似乎是由凝血介导的血小板消耗引起的，而其余1例患儿被诊断为特发性血小板减少性紫癜。在2例严重凝血介导的血小板减少（低于50,000/mm³）患儿中，有1例出现冠状动脉瘤且持续超过1年。