Hicks R V, Melish M E
Pediatr Clin North Am. 1986 Oct;33(5):1151-75. doi: 10.1016/s0031-3955(16)36113-2.
Kawasaki's syndrome is an acute, largely self-limited multisystem vasculitis of childhood with prominent rheumatic complaints, involving both the heart and the joints. Although the etiologic agent has not been discovered, the evidence appears overwhelming that a microbial agent is the responsible trigger for this multisystem disease. Immunologically mediated phenomena appear to be important in the development of the significant complications of KS carditis, coronary vasculitis, and arthritis. Although truly effective therapy is not yet available, there is an exciting possibility that immunologic treatment may have beneficial effect. More effective preventive and therapeutic methods will become available when the elusive agent is discovered.
川崎病是一种急性、大多为自限性的儿童多系统血管炎，伴有明显的风湿性症状，累及心脏和关节。尽管病因尚未明确，但有压倒性的证据表明，微生物制剂是引发这种多系统疾病的原因。免疫介导现象在川崎病心脏炎、冠状动脉血管炎和关节炎等严重并发症的发展过程中似乎起着重要作用。虽然目前尚无真正有效的治疗方法，但免疫治疗可能产生有益效果，这是一个令人兴奋的可能性。当找到这种难以捉摸的病原体时，将会有更有效的预防和治疗方法。
