Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, USA.
, 760 Westwood Plz., Rm. 67-467, Los Angeles, CA, USA.
Child Psychiatry Hum Dev. 2022 Feb;53(1):3-15. doi: 10.1007/s10578-020-01111-4. Epub 2021 Jan 1.
This study describes impairment in academic, interpersonal, recreational, and family financial or occupational domains across children in three mutually exclusive diagnostic groups: ever diagnosed with Tourette syndrome (TS), attention-deficit/hyperactivity disorder (ADHD), and both disorders. In 2014, parents reported on impairment and diagnostic status of children aged 4-17 years (n = 3014). Weighted analysis and pairwise t-tests showed more children with ADHD (with or without TS) experienced impairment in overall school performance, writing, and mathematics, relative to children with TS but not ADHD. More children with TS and ADHD had problematic handwriting relative to children with ADHD but not TS. More children with TS and ADHD had problematic interpersonal relationships relative to those with ADHD but not TS. Children with TS and ADHD had higher mean impairment across domains than children with either TS or ADHD. Findings suggest assessing disorder-specific contributions to impairment could inform targeted interventions for TS and ADHD.
本研究描述了三个相互排斥的诊断组中儿童在学业、人际关系、娱乐和家庭经济或职业领域的障碍:曾被诊断为妥瑞氏症(TS)、注意力缺陷/多动障碍(ADHD),或两种疾病均被诊断。2014 年,家长报告了 4-17 岁儿童的障碍和诊断状况(n=3014)。加权分析和成对 t 检验显示,患有 ADHD(无论是否患有 TS)的儿童在总体学业成绩、写作和数学方面的障碍发生率高于仅患有 TS 的儿童,但与不患有 ADHD 的 TS 儿童无差异。患有 TS 和 ADHD 的儿童中,有书写问题的比例高于仅患有 ADHD 的儿童,但低于同时患有 TS 和 ADHD 的儿童。患有 TS 和 ADHD 的儿童在人际关系方面的问题比仅患有 ADHD 的儿童更为严重。患有 TS 和 ADHD 的儿童在所有领域的平均障碍得分均高于仅患有 TS 或 ADHD 的儿童。研究结果表明,评估特定疾病对障碍的影响可能有助于为 TS 和 ADHD 提供有针对性的干预措施。