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经皮椎间孔内镜椎间盘切除术治疗复发性腰椎间盘突出症的放射学危险因素:回顾性匹配病例对照研究。

Radiological risk factors for recurrent lumbar disc herniation after percutaneous transforaminal endoscopic discectomy: a retrospective matched case-control study.

机构信息

Department of Spine Surgery, School of Medicine, ZhongDa Hospital, Southeast University, Nanjing, 210009, Jiangsu, China.

出版信息

Eur Spine J. 2021 Apr;30(4):886-892. doi: 10.1007/s00586-020-06674-3. Epub 2021 Jan 1.

Abstract

PURPOSE

To investigate radiological risk factors for recurrent lumbar disc herniation (rLDH) after percutaneous transforaminal endoscopic discectomy (PTED).

METHODS

Patients who underwent PTED due to a single-level L4-L5 or L5-S1 disc herniation from January 2013 to May 2019 were enrolled in this study. A matched case-control design was carried out in a single institution. Cases were defined as those who developed rLDH, and controls were matched from those patients without rLDH according to corresponding clinical characteristics. The radiological parameters were compared between two groups. The radiological risk factors for rLDH after PTED were identified by univariate and multivariate logistic regression analysis.

RESULTS

A total of 2186 patients who underwent PTED at L4-L5 or L5-S1 level were enrolled in this study. Sixty-eight patients were diagnosed with rLDH, and 136 patients were selected from the remaining 2118 nonrecurrent patients as matched controls. Univariate analysis demonstrated that herniation type (P = 0.009), surgical-level disc degeneration (P < 0.001), adjacent-level disc degeneration (P = 0.017), disc height index (DHI) (P = 0.003), and sagittal range of motion (sROM) (P < 0.001) were significantly related to rLDH. Multiple logistic regression analysis showed that low grade of surgical-level disc degeneration (P < 0.001), senior grade of adjacent-level disc degeneration (P < 0.001), a high DHI (P = 0.012), and a large sROM (P < 0.001) were the radiological independent risk factors.

CONCLUSION

This study showed that low grade of surgical-level disc degeneration, senior grade of adjacent-level disc degeneration, a high DHI, and a large sROM were the radiological independent risk factors for rLDH after PTED.

摘要

目的

探讨经皮椎间孔内窥镜椎间盘切除术(PTED)后复发性腰椎间盘突出症(rLDH)的放射学危险因素。

方法

本研究纳入了 2013 年 1 月至 2019 年 5 月因单节段 L4-L5 或 L5-S1 椎间盘突出症接受 PTED 的患者。在单中心进行了匹配病例对照设计。病例组定义为出现 rLDH 的患者,对照组根据相应的临床特征从无 rLDH 的患者中匹配。比较两组的放射学参数。采用单因素和多因素 logistic 回归分析确定 PTED 后 rLDH 的放射学危险因素。

结果

本研究共纳入 2186 例接受 L4-L5 或 L5-S1 水平 PTED 的患者。68 例患者被诊断为 rLDH,从其余 2118 例无复发患者中选择 136 例作为匹配对照。单因素分析表明,突出类型(P = 0.009)、手术水平椎间盘退变(P < 0.001)、相邻水平椎间盘退变(P = 0.017)、椎间盘高度指数(DHI)(P = 0.003)和矢状位活动范围(sROM)(P < 0.001)与 rLDH 显著相关。多因素 logistic 回归分析显示,手术水平椎间盘退变程度低(P < 0.001)、相邻水平椎间盘退变程度高(P < 0.001)、DHI 高(P = 0.012)和 sROM 大(P < 0.001)是 PTED 后 rLDH 的放射学独立危险因素。

结论

本研究表明,手术水平椎间盘退变程度低、相邻水平椎间盘退变程度高、DHI 高、sROM 大是 PTED 后 rLDH 的放射学独立危险因素。

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