Department of Radiology, The Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, HA7 4LP, UK.
Skeletal Radiol. 2021 Jul;50(7):1275-1290. doi: 10.1007/s00256-020-03682-8. Epub 2021 Jan 2.
Paget's sarcoma is a rare and particularly aggressive tumour arising within pagetic bone, affecting approximately 1% of patients with Paget's disease during the course of their disease. Most of these tumours are osteosarcomas, but the age profile, skeletal distribution and clinical outcomes differ considerably from conventional osteosarcoma. In this review, we outline the clinical, radiographic/CT, scintigraphic and magnetic resonance imaging features of Paget's sarcoma. We also review the neoplastic and non-neoplastic mimics of Paget's sarcoma that should be considered in the differential diagnosis when encountering an aggressive lesion within pagetic bone.
佩吉特氏肉瘤是一种罕见的、特别具有侵袭性的肿瘤，发生于佩吉特氏病的骨骼中，在疾病进程中约有 1%的佩吉特氏病患者会发生这种肿瘤。这些肿瘤大多数是骨肉瘤，但在年龄分布、骨骼分布和临床结果方面与传统的骨肉瘤有很大的不同。在这篇综述中，我们概述了佩吉特氏肉瘤的临床、影像学/CT、闪烁扫描和磁共振成像特征。我们还回顾了佩吉特氏肉瘤的肿瘤和非肿瘤性类似物，在遇到佩吉特氏病骨骼中的侵袭性病变时，应考虑将这些类似物纳入鉴别诊断。
