Programa de Pós-Graduação em Medicina Translacional, Universidade Federal de São Paulo (UNIFESP) São Paulo, São Paulo, Brazil.
Departamento de Psicobiologia, Universidade Federal de São Paulo (UNIFESP) São Paulo, São Paulo, Brazil.
J Cosmet Dermatol. 2021 Apr;20(4):1088-1090. doi: 10.1111/jocd.13929. Epub 2021 Jan 12.
Telogen effluvium (TE), a common hair disease, is supposed to be related to stress, which could be secondary to poor sleep. We call attention to the current COVID-19 pandemic, that is leading to an increase in the prevalence of sleep disturbances, and as a consequence, higher states of stress and anxiety, which are possible triggers for TE. In parallel, trichodynia is a sensorial symptom that is commonly related with hair diseases, including TE. We argue that substance P, a neuropeptide that has participation in the neuroinflammation and in the sleep regulation, may play a possible role in this scalp paresthesia. We suggest that there may be an association between this substrate and sleep, which can aggravate trichodynia and TE. Further studies on this subject could provide more evidence on these relationships, and help to improve the patients' quality of life and management of the condition.
休止期脱发（TE）是一种常见的毛发疾病，据推测与压力有关，而压力可能是睡眠质量差引起的。我们注意到当前的 COVID-19 大流行导致睡眠障碍的患病率增加，因此压力和焦虑的状态也随之上升，这可能是 TE 的触发因素。与此同时，头皮感觉异常是一种与包括 TE 在内的毛发疾病相关的感觉症状。我们认为 P 物质（一种参与神经炎症和睡眠调节的神经肽）可能在这种头皮感觉异常中发挥作用。我们提出，这种物质可能与睡眠有关，这可能会加重头皮感觉异常和 TE。关于这个问题的进一步研究可以提供更多关于这些关系的证据，并有助于改善患者的生活质量和疾病的管理。
