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掺入发射α粒子的放射性核素导致晶状体受照射及诱发白内障的可能性。

The potential for irradiation of the lens and cataract induction by incorporated alpha-emitting radionuclides.

作者信息

Taylor D M, Thorne M C

机构信息

Kernforschungszentrum Karlsruhe, Institute for Genetics and Toxicology, Federal Republic of Germany.

出版信息

Health Phys. 1988 Feb;54(2):171-9. doi: 10.1097/00004032-198802000-00006.

DOI:10.1097/00004032-198802000-00006
PMID:3338915
Abstract

Data on the uptake and retention of Ra and Pu in ocular tissues are reviewed. These data were used to calculate alpha radiation doses to the lens of the eye for patients injected with 224Ra and for individuals exposed to one annual limit on intake (ALI) per year of 224Ra, 226Ra, 228Ra and 239Pu for a period of 50 y. On the basis of this analysis, it is concluded that the induction of lens opacity should not be the factor limiting intake of any radioisotope of Pu or for 224Ra or 226Ra. However, for 228Ra the dose lies within the range of doses received by 224Ra patients who have developed cataracts.

摘要

本文综述了镭(Ra)和钚(Pu)在眼部组织中的摄取和滞留数据。利用这些数据计算了接受224Ra注射的患者以及每年摄入224Ra、226Ra、228Ra和239Pu达到一个年摄入量限值(ALI),持续50年的个体眼部晶状体所接受的α辐射剂量。基于此分析得出结论,晶状体混浊的诱发不应成为限制任何钚的放射性同位素或224Ra或226Ra摄入量的因素。然而,对于228Ra,其剂量处于已患白内障的224Ra患者所接受剂量的范围内。

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