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纳米技术在解决口服药物传递挑战中的相关性:观点综述。

Relevance of Nanotechnology in Solving Oral Drug Delivery Challenges: A Perspective Review.

机构信息

D.S.T.S. Mandal's College of Pharmacy, Solapur-413004, Maharastra, India.

MMES's Bangi College of Pharmacy, Vijayapur-586101, Karnataka, India.

出版信息

Crit Rev Ther Drug Carrier Syst. 2020;37(5):407-434. doi: 10.1615/CritRevTherDrugCarrierSyst.2020032583.

DOI:10.1615/CritRevTherDrugCarrierSyst.2020032583
PMID:33389846
Abstract

Nanotechnology is opening up new opportunities in drug delivery, including oral delivery, and it may reduce toxicity and increase drug ability. Presently, researchers are expanding their knowledge in the development of oral nanomedicine to extend the scope of oral drug delivery and exhibit excellent platforms for drug transportation, target, and controlled release. The present review is an attempt to define updated oral nanostructured systems for the delivery of a wide range of drugs. The review also focuses on the use of different polymeric and other materials, technologies adopted, and benefits/drawbacks of delivery systems.

摘要

纳米技术在药物输送领域开辟了新的机遇,包括口服输送,它可能降低毒性并提高药物效力。目前,研究人员正在扩大他们在口服纳米医学开发方面的知识,以扩大口服药物输送的范围,并展示出色的药物输送、靶向和控制释放平台。本综述旨在定义用于输送广泛药物的更新型口服纳米结构系统。该综述还重点介绍了不同聚合物和其他材料的使用、采用的技术以及输送系统的优缺点。

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