Rediker D E, Block P C, Abascal V M, Palacios I F
Department of Medicine (Cardiac Unit), Massachusetts General Hospital, Boston 02114.
J Am Coll Cardiol. 1988 Feb;11(2):252-6. doi: 10.1016/0735-1097(88)90088-5.
Mitral balloon valvuloplasty was performed in 14 patients with recurrent mitral stenosis 16.9 +/- 1.8 years (range 6 to 30) after surgical commissurotomy. There were 13 women and 1 man with a mean age of 55 +/- 4 years (range 23 to 73). Mitral balloon valvuloplasty resulted in an increase in mitral valve area from 0.8 +/- 0.1 to 1.7 +/- 0.2 cm2 (p = 0.001), a decrease in mean mitral diastolic pressure gradient from 15 +/- 2 to 7 +/- 1 mm Hg (p = 0.001) and an increase in cardiac output from 3.4 +/- 0.3 to 3.9 +/- 0.3 liters/min (p = 0.03). No deaths, strokes, vascular complications or conduction abnormalities were observed. Mitral regurgitation developed or increased in severity in seven patients (50%). There was no evidence of significant left to right shunt through the atrial septal puncture site after mitral balloon valvuloplasty. A good result (defined as a mitral valve area greater than 1.0 cm2, an increase in mitral valve area greater than 25% and a mean gradient less than 10 mm Hg) was achieved in 9 (64%) of the 14 patients. A subgroup of four patients who had a superior result (increase in mitral valve area of 1.7 +/- 0.2 versus 0.5 +/- 0.1 cm2 in the other 10 patients, p = 0.004) was identified. These patients had less echocardiographic evidence of rheumatic mitral valve damage and were the only patients who had sinus rhythm. They were also younger, less debilitated and had a lower grade of fluoroscopic valve calcification compared with the other patients. Thus, mitral balloon valvuloplasty is a safe and effective procedure for patients with recurrent mitral stenosis after surgical commissurotomy.(ABSTRACT TRUNCATED AT 250 WORDS)
14例接受过二尖瓣交界切开术的复发性二尖瓣狭窄患者在术后16.9±1.8年(范围6至30年)接受了二尖瓣球囊瓣膜成形术。其中有13名女性和1名男性,平均年龄为55±4岁(范围23至73岁)。二尖瓣球囊瓣膜成形术使二尖瓣瓣口面积从0.8±0.1增加至1.7±0.2平方厘米(p = 0.001),二尖瓣平均舒张期压力阶差从15±2降至7±1毫米汞柱(p = 0.001),心输出量从3.4±0.3增加至3.9±0.3升/分钟(p = 0.03)。未观察到死亡、中风、血管并发症或传导异常。7例患者(50%)出现二尖瓣反流或反流程度加重。二尖瓣球囊瓣膜成形术后,未发现有明显的经房间隔穿刺部位从左向右分流的证据。14例患者中有9例(64%)取得了良好的效果(定义为二尖瓣瓣口面积大于1.0平方厘米、二尖瓣瓣口面积增加大于25%且平均压力阶差小于10毫米汞柱)。确定了一个有更好效果的亚组,包括4例患者(二尖瓣瓣口面积增加1.7±0.2,而其他10例患者为0.5±0.1平方厘米,p = 0.004)。这些患者超声心动图显示的风湿性二尖瓣损害证据较少,且是仅有的窦性心律患者。与其他患者相比,他们年龄更小、身体状况更好且荧光透视下瓣膜钙化程度更低。因此,二尖瓣球囊瓣膜成形术对于二尖瓣交界切开术后复发性二尖瓣狭窄患者是一种安全有效的手术。(摘要截断于250字)