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免疫抑制成年患者的波特氏浮肿性肿瘤:病例报告及文献系统综述

Pott's puffy tumour in an immunosuppressed adult: case report and systematic review of literature.

作者信息

Paw Ekta, Ong Chelsea T W, Vangaveti Venkat

机构信息

James Cook University, College of Medicine and Dentistry, Townsville, Queensland 4811, Australia.

Mater Hospital Pimlico, Department of Surgery, Townsville, Queensland 4812, Australia.

出版信息

J Surg Case Rep. 2020 Dec 28;2020(12):rjaa528. doi: 10.1093/jscr/rjaa528. eCollection 2020 Dec.

DOI:10.1093/jscr/rjaa528
PMID:33391653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7769593/
Abstract

This case is of a 34-year-old immunocompromised male with Pott's puffy tumour, which was treated with antibiotics and endoscopic sinus surgery. Pott's puffy tumour is typically a complication of frontal sinusitis in children and immunocompromise can be a precipitating factor. A search was conducted of Embase, Medline, CINAHL, Cochrane, Google Scholar, Informit and Scopus of 'Pott's Puffy' and variations of this phrase. Initial 804 records were reviewed by title, abstract and full text. Of the unique papers identified, 155 only included paediatric patients and 128 included adult patients. After title, abstract and full-text review of 13 papers were identified describing Pott's puffy tumour in immunocompromised patients. Immunosuppression was noted as a risk factor in only a small number of cases, with diabetes mellitus being the most common. A few cases did note immunosuppression due to newer immunomodulatory agents being used for treatment of autoimmune conditions.

摘要

该病例为一名34岁的免疫功能低下男性,患有波特氏浮肿性肿瘤,接受了抗生素和鼻内镜鼻窦手术治疗。波特氏浮肿性肿瘤通常是儿童额窦炎的并发症,免疫功能低下可能是一个诱发因素。我们对Embase、Medline、CINAHL、Cochrane、谷歌学术、Informit和Scopus数据库进行了检索,搜索词为“波特氏浮肿”及其变体。初步检索到804条记录,通过标题、摘要和全文进行了筛选。在筛选出的独特文献中,155篇仅纳入了儿科患者,128篇纳入了成年患者。在对13篇描述免疫功能低下患者波特氏浮肿性肿瘤的文献进行标题、摘要和全文审查后,发现仅有少数病例将免疫抑制作为危险因素,最常见的是糖尿病。少数病例确实提到由于使用新型免疫调节药物治疗自身免疫性疾病而导致免疫抑制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cca/7769593/90652b7b9f18/rjaa528f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cca/7769593/4d885837f76e/rjaa528f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cca/7769593/b2eed1f7ffd8/rjaa528f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cca/7769593/90652b7b9f18/rjaa528f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cca/7769593/4d885837f76e/rjaa528f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cca/7769593/b2eed1f7ffd8/rjaa528f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cca/7769593/90652b7b9f18/rjaa528f3.jpg

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引用本文的文献

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Pott's Puffy Tumor in the Adult Population: Systematic Review and Meta-Analysis of Case Reports.成人人群中的波特氏浮肿性肿瘤:病例报告的系统评价与荟萃分析
J Clin Med. 2025 Jun 8;14(12):4062. doi: 10.3390/jcm14124062.
2
A Systematic Review of Intracranial Complications in Adults with Pott Puffy Tumor over Four Decades.四十年来成人波特氏浮肿性肿瘤颅内并发症的系统评价
Brain Sci. 2023 Mar 30;13(4):587. doi: 10.3390/brainsci13040587.

本文引用的文献

1
Recurrent Pott's Puffy Tumor Treated With Anterior Skull Base Resection With Reconstruction of the Anterolateral Thigh Flap.采用前颅底切除术并重建股前外侧皮瓣治疗复发性波特氏浮肿性肿瘤。
J Craniofac Surg. 2019 Jan;30(1):e94-e96. doi: 10.1097/SCS.0000000000005100.
2
When the diagnosis is written on the forehead.
Eur J Intern Med. 2018 Jan;47:e1-e2. doi: 10.1016/j.ejim.2017.04.025. Epub 2017 May 6.
3
A 60-year-old man with forehead swelling.
Cleve Clin J Med. 2016 Feb;83(2):95-6. doi: 10.3949/ccjm.83a.15011.
4
Pott's puffy tumour and intracranial complications of frontal sinusitis in pregnancy.妊娠期间的波特氏肿及额窦炎的颅内并发症
J Laryngol Otol. 2013 Jan;127 Suppl 1:S35-8. doi: 10.1017/S0022215112001673. Epub 2012 Aug 15.
5
Evaluation of adult Pott's puffy tumor: our five cases and 27 literature cases.成人波特氏脓肿的评估:我们的 5 个病例和 27 篇文献病例。
Laryngoscope. 2012 Nov;122(11):2382-8. doi: 10.1002/lary.23490. Epub 2012 Aug 2.
6
Pott's puffy tumour mimicking preseptal cellulitis.
Clin Exp Optom. 2008 Jul;91(4):400-2. doi: 10.1111/j.1444-0938.2007.00234.x.
7
Pott's puffy tumour caused by mucormycosis.由毛霉菌病引起的波特氏浮肿性肿瘤。
J Laryngol Otol. 2005 Aug;119(8):643-5. doi: 10.1258/0022215054516304.
8
Pott's puffy tumor of the vertex years after trauma in a diabetic patient: case report.
Neurocirugia (Astur). 2005 Feb;16(1):54-7. doi: 10.1016/s1130-1473(05)70435-8.
9
Frontal sinus cutaneous fistula: a complication of Pott's puffy tumor.额窦皮肤瘘:波特氏浮肿性骨炎的一种并发症。
Otolaryngol Head Neck Surg. 2004 Apr;130(4):490-1. doi: 10.1016/j.otohns.2003.10.006.
10
Headache caused by Pott's puffy tumor.波特氏头皮肿胀性脓肿所致头痛
Headache. 2003 Sep;43(8):916. doi: 10.1046/j.1526-4610.2003.03173.x.