Hickson Warren, Mayers Pat M
Department of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Department of Health and Rehabilitation Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Health SA. 2020 Dec 14;25:1458. doi: 10.4102/hsag.v25i0.1458. eCollection 2020.
Antiretroviral therapy (ART), the only effective treatment for human immunodeficiency virus (HIV), requires excellent long-term compliance. Poor levels of adherence to ART, especially amongst adolescents and young adults in South Africa, have been reported.
This study aimed to explore how young people become motivated to take their HIV medication (ART) and how the need for adherence is communicated.
The study was conducted in a peri-urban township in the Western Cape, South Africa.
A qualitative grounded theory approach was employed. Eighty young people were purposively recruited. Participant observation, focus groups and semi-structured interviews were utilised to explore how effective ART adherence messages are in motivating adherence amongst young people and how they would like ART adherence to be communicated to them. All interviews and focus groups were transcribed and analysed by using cross-comparison analysis. Measures to ensure trustworthiness were established and ethical considerations were adhered to.
Young people's adherence motivation was an outcome of reconnecting to one or more trusted significant other(s) from within their belonging group, who accepted and supported them, which in turn affirmed their prior belonging identities of son, daughter, other family member or close friend. This facilitated reconnection to their present and future hopes, which in turn increased their motivation to live and to adhere to treatment.
The findings highlight the need for the development of more effective communication strategies, which facilitate and support young people's reconnection to trusted members of their belonging groups, and also help belonging group members to accept, affirm and support adherence.
抗逆转录病毒疗法（ART）是治疗人类免疫缺陷病毒（HIV）的唯一有效方法，需要长期保持良好的依从性。据报道，南非青少年和年轻人对抗逆转录病毒疗法的依从性较差。
本研究旨在探讨年轻人如何产生服用抗HIV药物（ART）的动机，以及如何传达坚持服药的必要性。
该研究在南非西开普省的一个城郊乡镇进行。
采用定性扎根理论方法。有目的地招募了80名年轻人。通过参与观察、焦点小组和半结构化访谈，探讨抗逆转录病毒疗法依从性信息在激发年轻人依从性方面的效果，以及他们希望如何接收关于抗逆转录病毒疗法依从性的信息。所有访谈和焦点小组都进行了转录，并使用交叉比较分析进行分析。建立了确保可信度的措施，并遵循了伦理考量。
年轻人的依从动机是与所属群体中一个或多个值得信赖的重要他人重新建立联系的结果，这些人接受并支持他们，这反过来又确认了他们作为儿子、女儿、其他家庭成员或亲密朋友的先前所属身份。这有助于他们重新与自己现在和未来的希望建立联系，进而增强了他们生活和坚持治疗的动力。
研究结果强调需要制定更有效的沟通策略，以促进和支持年轻人与所属群体中值得信赖的成员重新建立联系，并帮助所属群体成员接受、确认和支持坚持治疗。
