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老年疗养院居民脱水的风险因素。

Risk factors for dehydration among elderly nursing home residents.

作者信息

Lavizzo-Mourey R, Johnson J, Stolley P

机构信息

Section of General Medicine, University of Pennsylvania, Philadelphia 19104.

出版信息

J Am Geriatr Soc. 1988 Mar;36(3):213-8. doi: 10.1111/j.1532-5415.1988.tb01803.x.

Abstract

Dehydration is the most common fluid and electrolyte disorder among the elderly, yet risk factors are not known. This study identifies risk factors for dehydration in acutely ill nursing home residents. All 339 elderly resident of two nursing homes who developed an acute illness requiring hospitalization during 1984 were included in the study. The 173 patients having a serum Na less than 150 mg/dL and blood urea nitrogen to creatinine ratio (BUN:Cre) less than 20 were designated controls; 91 patients having a serum Na greater than 150 mg/dL or a serum BUN:Cre greater than 25 were designated cases. Odds ratios (OR) and confidence intervals were calculated for age, sex, chronic conditions, acute illnesses, medications, functional status measures, and season. Acutely ill dehydrated patients were female (OR, 3.3); over 85 years old (OR, 2.2); had more than four chronic conditions (OR, 4.0); took more than four medications (OR, 2.8); and were bedridden (OR, 2.9). Among the most severely dehydrated (serum Na greater than 150 mg/dL and BUN:Cre greater than 25), the odds ratios for the above factors were strengthened and other factors, such as inability to feed oneself and type of acute diagnosis, emerged as risk factors. Among the variables unrelated to functional status, laxatives (OR, 3.2) and chronic infections (OR, 1.8) were risk factors. We conclude that a group at high risk for dehydration can be defined and that they are better characterized by the number of chronic diseases and debilitated functional status than by acute disease processes.

摘要

脱水是老年人中最常见的液体和电解质紊乱,但风险因素尚不清楚。本研究确定了急性病疗养院居民脱水的风险因素。1984年期间两所疗养院中所有339名因急性病需要住院治疗的老年居民都纳入了研究。血清钠低于150mg/dL且血尿素氮与肌酐比值(BUN:Cre)低于20的173例患者被指定为对照组;血清钠高于150mg/dL或血清BUN:Cre高于25的91例患者被指定为病例组。计算了年龄、性别、慢性病、急性病、药物、功能状态指标和季节的比值比(OR)及置信区间。急性病脱水患者为女性(OR,3.3);年龄超过85岁(OR,2.2);患有四种以上慢性病(OR,4.0);服用四种以上药物(OR,2.8);卧床不起(OR,2.9)。在脱水最严重的患者(血清钠高于150mg/dL且BUN:Cre高于25)中,上述因素的比值比增强,其他因素如无法自行进食和急性诊断类型也成为风险因素。在与功能状态无关的变量中,泻药(OR,3.2)和慢性感染(OR,1.8)是风险因素。我们得出结论,可确定一组脱水高危人群,与其用急性疾病过程来描述,用慢性病数量和衰弱的功能状态来描述他们更为恰当。

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