Wolf-Klein G P, Siverstone F A, Brod M S, Levy A, Foley C J, Termotto V, Breuer J
Department of Medicine, State University of New York, Stony Brook.
J Am Geriatr Soc. 1988 Mar;36(3):219-24. doi: 10.1111/j.1532-5415.1988.tb01804.x.
At an active outpatient geriatric program the gerontological team observed that Alzheimer patients appear to have fewer physical ailments than other elderly patients. To test this hypothesis, we reviewed a sample of 348 clinic patients. One hundred forty-three had a normal mental status; 75 had Alzheimer's disease as defined by DSM-III criteria; 139 had an abnormal mental status attributed to other etiologies. The number of diagnoses was compiled in each of the three groups. The average number of diagnoses in the nondemented group was 5.0 in males, 5.4 in females. In the non-Alzheimer abnormal mental status group, the average number was 5.5 in males, 4.6 in females. In contrast, the number of diagnoses in the Alzheimer group was 2.9 in males and 2.8 in females (P less than 0.0001). Cardiovascular diseases, hypertension, and cerebrovascular accidents were less frequent in the Alzheimer population. This study suggests that Alzheimer patients are physically healthier than non-Alzheimer elderly patients.
在一个活跃的门诊老年病项目中，老年病团队观察到，与其他老年患者相比，阿尔茨海默病患者似乎身体疾病较少。为了验证这一假设，我们回顾了348名门诊患者的样本。其中143人精神状态正常；75人根据《精神疾病诊断与统计手册》第三版（DSM-III）标准被诊断为患有阿尔茨海默病；139人精神状态异常，病因各异。我们统计了三组患者各自的诊断数量。非痴呆组男性的平均诊断数为5.0，女性为5.4。在非阿尔茨海默病精神状态异常组中，男性的平均诊断数为5.5，女性为4.6。相比之下，阿尔茨海默病组男性的诊断数为2.9，女性为2.8（P<0.0001）。心血管疾病、高血压和脑血管意外在阿尔茨海默病患者中更为少见。这项研究表明，阿尔茨海默病患者在身体上比非阿尔茨海默病老年患者更健康。
