Tezuka Masato, Mizusawa Hiroya, Tsukada Manabu, Mimura Yuji, Shimizu Takaaki, Kobayashi Aya, Takahashi Yasufumi, Maejima Toshitaka
Department of Urology National Hospital Organization Shinshu Ueda Medical Center Ueda Nagano Japan.
Department of Dermatology National Hospital Organization Shinshu Ueda Medical Center Ueda Nagano Japan.
IJU Case Rep. 2020 May 26;3(4):133-136. doi: 10.1002/iju5.12166. eCollection 2020 Jul.
Calciphylaxis is characterized by marked vascular calcification and painful skin ulcers, and it has a poor prognosis.
The patient was a 72-year-old male. He was referred for penile pain. He had a 4-year history of dialysis therapy under a diagnosis of diabetic nephropathy. Black and yellow necrosis was observed involving the entire glans, accompanying severe pain. Computed tomography revealed marked calcification involving the thoracoabdominal aorta to iliac arteries, the dorsal artery of the penis and the corpus cavernosum, leading to a diagnosis of calciphylaxis. Penile pain gradually exacerbated and partial penectomy was performed. After surgery, penile pain promptly subsided. Pathological examination confirmed marked calcification of the microvascular wall and narrowing of the lumen.
We reviewed 15 Japanese patients with calciphylaxis who had undergone penile surgery. Surgical treatment was considered to be effective at relieving penile pain, but the prognosis remained poor.
钙化防御的特征是明显的血管钙化和疼痛性皮肤溃疡，预后较差。
患者为一名72岁男性。因阴茎疼痛前来就诊。他有4年的透析治疗史，诊断为糖尿病肾病。观察到整个龟头出现黑色和黄色坏死，并伴有剧烈疼痛。计算机断层扫描显示，从胸主动脉到髂动脉、阴茎背动脉和海绵体均有明显钙化，诊断为钙化防御。阴茎疼痛逐渐加重，遂行部分阴茎切除术。术后，阴茎疼痛立即缓解。病理检查证实微血管壁明显钙化，管腔狭窄。
我们回顾了15例接受阴茎手术的日本钙化防御患者。手术治疗被认为对缓解阴茎疼痛有效，但预后仍然较差。
